Endovesical Metastasis of a Colic Adenocarcinoma: A Case Report

M. Bouziane, Omar Mouni, W. Kaikani, M. Kassimi, R. Rabii, A. Albouzidi
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Abstract

Background: Bladder infiltration by neighbourhood tumors is a common situation and can be found in prostate, colo-rectum and genital tumours in women. The main mechanism is a direct invasion of the bladder by the tumor. Intraluminal bladder metastases from distant primary tumors remain exceptional. Patient: We report the case of a 56-year-old patient without any particular medical history initially admitted for an occlusion caused by a transverse colic tumor. The patient did not have clinically haematuria and the initial scan did not show a location or abnormality in the bladder. Initial surgical exploration did not find peritoneal or bladder abnormalities. The patient's evolution will be marked by the appearance of bladder thickening at a distance from the primary tumor and peritoneal carcinosis. The immunohistochemical study in addition to the anatomopathological examination resulted in positive marking of the chorion tubes by anti CDX2 and anti CK 20 and positive marking of surface vesical epithelium by anti P63, anti GATTA3 and anti CK7 which confirmed the colorectal origin of endo-vesical metastasis. Conclusion: We will try through this case report and a review of literature to shed light on this unusual situation and it is important to keep in mind the possibility of remote metastatic location at the bladder of another primary tumor.
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结肠腺癌腔内转移1例报告
背景:膀胱邻域肿瘤浸润是一种常见的情况,可在女性前列腺、结直肠和生殖器肿瘤中发现。其主要机制是肿瘤直接侵入膀胱。远端原发肿瘤的膀胱腔内转移仍然是罕见的。病人:我们报告一个56岁的病人,没有任何特殊的病史,最初入院的闭塞引起的横向结肠肿瘤。患者没有临床血尿,初始扫描未显示膀胱的位置或异常。最初的手术探查未发现腹膜或膀胱异常。在原发肿瘤和腹膜癌远处出现膀胱增厚是患者病情发展的标志。免疫组化及解剖病理检查显示绒毛膜管被抗CDX2和抗ck20标记阳性,膀胱表面上皮被抗P63、抗GATTA3和抗CK7标记阳性,证实了膀胱内转移的结直肠起源。结论:我们将尝试通过本病例报告和文献回顾来阐明这种不寻常的情况,重要的是要记住另一原发肿瘤在膀胱远处转移的可能性。
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