Study of E. coli Pathogens Causing Intestinal Infections and Use of Bacteriophage Preparation-Coli Phage

T. Gabisonia, M. Loladze, M. Zarnadze, N. Kekenadze, Mariam Lomidze, N. Tamarashvili, G. Gabisonia, T. Beridze, M. Pkhaladze, R. Mirzikashvili, Irakli Chkhetia
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Abstract

According to the data of World Health Organization (WHO) about 2 billion of people get sick with intestinal infections annually. The pathogens which spread through food and water are the main causes of the sickness and mortality; they lead to death of about 1.8 million each year. Resulting from the mentioned problem, it carries particular importance to conduct microbiological and molecular research of bacterial pathogens causing intestinal infections. One of the main pathogens, which spread through waters, is variety of Salmonella, pathogenically Escherichia coli and Shigella. Monitoring the food and water related pathogens would facilitate the process of downsizing their frequency in the environment, which on its own would reduce the risk of spreading diseases caused by the mentioned pathogen amongst humans. Early identification of these pathogens has the vital importance for quick and effective treatment.
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大肠杆菌致病菌引起肠道感染的研究及噬菌体制剂-大肠杆菌噬菌体的应用
根据世界卫生组织(WHO)的数据,每年约有20亿人患有肠道感染。通过食物和水传播的病原体是致病和死亡的主要原因;它们每年导致约180万人死亡。因此,对引起肠道感染的细菌病原体进行微生物学和分子研究就显得尤为重要。通过水体传播的主要病原体之一是多种沙门氏菌、致病性大肠杆菌和志贺氏菌。监测与食物和水有关的病原体将有助于减少其在环境中出现的频率,这本身就会减少由上述病原体引起的疾病在人类之间传播的风险。这些病原体的早期识别对于快速有效的治疗至关重要。
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