Nano Science in Pulmonary Drug Delivery

B. Prajapati, Umang Varia
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Abstract

Respiratory diseases are a common disease with high incidence all over the world, pose a serious threat to human health and are considered to be an economic and social burden. The application of nanotechnology in drug delivery systems has created new treatments for respiratory diseases. In this regard, this review has systematically introduced the physicochemical properties of nanoparticles (NP). We have reviewed the current state of research on various Nano carriers in the treatment of respiratory diseases, including liposomes, solid lipid Nano carriers, and polymer Nano carriers. The application of nanotechnology overcomes some of the deficiencies inherent in drugs and offers endless possibilities for the development of drugs for the treatment of respiratory diseases. However, most of the relevant research is in the preclinical stage and the assessment of safety remains a difficult task. Future research is needed to focus on changes in the performance, molecular mechanisms, and potential toxicity of therapeutic Nano medicines.
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纳米科学在肺部给药
呼吸系统疾病是世界范围内高发的常见病,对人类健康构成严重威胁,是经济和社会负担。纳米技术在药物输送系统中的应用为呼吸系统疾病创造了新的治疗方法。在这方面,本文系统地介绍了纳米颗粒(NP)的理化性质。本文综述了各种纳米载体在呼吸系统疾病治疗中的研究现状,包括脂质体、固体脂质纳米载体和聚合物纳米载体。纳米技术的应用克服了药物固有的一些缺陷,为开发治疗呼吸系统疾病的药物提供了无限的可能性。然而,相关研究大多处于临床前阶段,安全性评估仍然是一项艰巨的任务。未来的研究需要关注治疗性纳米药物的性能、分子机制和潜在毒性的变化。
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