Approach to Subclinical Hypothyroidism in Adults

Jesús Nicolás Larco Coloma, Nicolás Larco Noboa
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Abstract

Thyroid pathology is the morphofunctional evolution of the thyroid glands that leads to different types of clinical pictures. Within it is subclinical hypothyroidism, which is a biochemical alteration due to the elevation of thyroid-stimulating hormone (TSH) between 4.5 to 10 mUI that can occur with or without symptoms of multifactorial origin. The worldwide prevalence is 4-10% and Latin America 15-25%. 90% of patients with this pathology do not require treatment, but in turn there is an overmedicalization and underdiagnosis of it. This bibliographic review analyzes from its morphofunctional changes towards clinical criteria for a comprehensive approach to subclinical hypothyroidism, where we have an individualization by its comorbidities, age group, diagnostic algorithm, follow-up and differentiated treatment according to recent studies within this pathology. Therefore, an adequate diagnosis, follow-up and treatment provides a better lifestyle for patients.
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成人亚临床甲状腺功能减退症的探讨
甲状腺病理是甲状腺的形态功能演变,导致不同类型的临床图片。其中包括亚临床甲状腺功能减退,这是由于促甲状腺激素(TSH)在4.5至10 mUI之间升高而引起的生化改变,可伴有或不伴有多因素起源的症状。全球患病率为4-10%,拉丁美洲为15-25%。90%患有这种病理的患者不需要治疗,但反过来又存在过度用药和诊断不足。这篇文献综述从亚临床甲状腺功能减退症的形态功能变化到临床标准的综合方法分析,其中我们根据其合并症、年龄组、诊断算法、随访和根据该病理学的最新研究进行个体化治疗。因此,充分的诊断、随访和治疗可以为患者提供更好的生活方式。
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32
审稿时长
11 weeks
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