Meta-Analysis the Association between Chronic Obstructive Pulmonary Disease Comorbidity and COVID-19 Mortality

Abstract

disease that hit the world community at the end of 2019. The risk of death from COVID-19 is highly dependent on age and previous health conditions. COVID-19 severe and critical symptoms are more commonly found in older patients and patients who have chronic comor­bidities such as cardio­vascular disease, hyper­tension, diabetes, including COPD. This study aims to deter­mine the relationship between COPD and mortality of COVID-19 patients in hospitals. Subjects and Method: This a meta-analysis study using the PRISMA flowchart guidelines. The article search process was carried out between 2020-2021 using databases from PubMed, Google Scholar, Science Direct, BMJ Garuda, SINTA, and National Library. Based on the database, there were 9 articles that met the inclusion criteria. The analysis was carried out using RevMan 5.3 software. Results: A total of 9 articles reviewed in the meta-analysis showed that comorbid COPD had a statistically significant association with hos­pital mortality of COVID-19 patients (aOR = 1.51; 95% CI= 1.21 to 1.9; p < 0.001). Conclusion: COPD comorbidities have an increased risk of dying of COVID-19 patients in hospital. Keywords: CPOD, COVID-19, death, meta-analysis Correspondence:  Pamogsa Ratri Adha Daniyar. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: pamogsadaniyar@gmail.com. Mobile: +62 852-9060-1552. Journal of Epidemiology and Public Health (2021), 06(02): 222-231 https://doi.org/10.26911/jepublichealth.2021.06.02.09