{"title":"Ayurveda treatment for granulomatosis with polyangiitis: A case report","authors":"Santosh Bhatted, D. Kabra","doi":"10.4103/jism.jism_41_22","DOIUrl":null,"url":null,"abstract":"Granulomatosis with polyangiitis (GPA) was formerly known as Wegener’s granulomatosis. As its name implies, the disease is associated with a necrotizing granulomatous inflammation with vasculitis of small and medium blood vessels induced by antineutrophil cytoplasmic antibodies (ANCA). Here, we present a case of a 42-year-old woman with severe arthralgia associated with fever and obstructive uropathy. Blood investigations revealed a high level of C-ANCA, C-reactive protein, erythrocyte sedimentation rate, and reduced hemoglobin level. She had a history of rheumatic heart disease in the childhood. The patient was treated with Ayurvedic oral drugs for 3 months. After 1 month of follow-up period, the patient showed a significant improvement in presenting symptoms as well as laboratory investigations. There was a significant reduction in swelling and tenderness over both ankle joints. Presently, the patient is stable with Ayurvedic medications. The case study shows a ray of hope toward the management of GPA with holistic Ayurveda medications with satisfactory outcome and contentment of the patient. However, more studies should be observed for definite conclusion.","PeriodicalId":16051,"journal":{"name":"Journal of Indian System of Medicine","volume":"47 1","pages":"196 - 199"},"PeriodicalIF":0.0000,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Indian System of Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jism.jism_41_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Granulomatosis with polyangiitis (GPA) was formerly known as Wegener’s granulomatosis. As its name implies, the disease is associated with a necrotizing granulomatous inflammation with vasculitis of small and medium blood vessels induced by antineutrophil cytoplasmic antibodies (ANCA). Here, we present a case of a 42-year-old woman with severe arthralgia associated with fever and obstructive uropathy. Blood investigations revealed a high level of C-ANCA, C-reactive protein, erythrocyte sedimentation rate, and reduced hemoglobin level. She had a history of rheumatic heart disease in the childhood. The patient was treated with Ayurvedic oral drugs for 3 months. After 1 month of follow-up period, the patient showed a significant improvement in presenting symptoms as well as laboratory investigations. There was a significant reduction in swelling and tenderness over both ankle joints. Presently, the patient is stable with Ayurvedic medications. The case study shows a ray of hope toward the management of GPA with holistic Ayurveda medications with satisfactory outcome and contentment of the patient. However, more studies should be observed for definite conclusion.