Tropisetron in the Prevention of Postoperative Nausea and Vomiting Induced by Patient-Controlled Epidural Analgesia in Gynopathic Patients:Observation of Curative Effects

中国药房 Pub Date : 2006-01-01 DOI:10.1097/00132586-200106000-00044

Gan Jian-hui

引用次数: 0

Abstract

OBJECTIVE:To observe the curative effect of tropisetron in the prevention of postoperative nausea and vomˉiting caused by patient-controlled epidural analgesia(PCEA)in gynopathic patients.METHODS:120patients who had unˉdergone patient-controlled epidural analgesia(PCEA)after gynopathic operation were randomly divided into2groups:60in group T were assigned to receive tropisetron,and60in group N as control,the incidences of nausea and vomiting in the two groups after medication were observed.RESULTS:There were significantly lower incidences of nausea and vomiting within48h in group T than in the placebo group(group N)(P0.05).CONCLUSIONS:Tropisetron is safe and effective in the prevention of PCEA in gynopathic patients.

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托司司琼预防妇科患者硬膜外自控镇痛术后恶心呕吐的疗效观察

目的:观察托咪司琼预防妇科患者术后患者自控硬膜外镇痛(PCEA)引起的恶心和呕吐的疗效。方法:将120例妇科手术后行患者自控硬膜外镇痛(PCEA)的患者随机分为2组，T组60例给予托司司琼治疗，N组60例作为对照，观察两组患者用药后恶心、呕吐的发生情况。结果:T组患者48h内恶心呕吐发生率显著低于安慰剂组(N组)(P0.05)。结论:托哌司琼预防妇科患者PCEA安全有效。

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来源期刊

中国药房

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27646

期刊介绍： China Pharmacy (bimonthly) is a national-level, open-access academic journal of pharmacy, founded in 1990, under the supervision of the National Health and Health Commission, and jointly sponsored by the China Hospital Association and the Affiliated Cancer Hospital of Chongqing University, with the aim of ‘navigating the medical and health care’. It has a wide influence in the industry. It was founded in 1990, and its readers are mainly professional and technical personnel of all levels and types working in the pharmacy department of hospitals, as well as personnel in drug development, production, operation, clinical application and supervision and management. The main columns include: Guidelines and Consensus (including industry guidelines, consensus, norms and related interpretations, etc.), Pharmaceutical Management (including research on pharmaceutical and health policies, management of hospital pharmacy departments, and management of social pharmacies/pharmacies, etc.), Pharmacy Research (including basic research on pharmacology, pharmacy, and drug analysis, etc.), Pharmacoeconomics (including economic evaluations of medicines, and studies related to health insurance payments, etc.), Drugs and Clinics (including studies on drug regimens, blood drug regimens, and clinical applications), and Drugs and Clinics ( Drugs and Clinics (including research on drug treatment protocols, blood concentration testing, clinical pharmacological studies, adverse reactions, etc.), Evidence-Based Pharmacy (including evaluation of clinical medication systems, evidence-based research, etc.), Pharmacists and Pharmacy Services (including research on hospital pharmacy service models, medication data analysis, prescription review, medication monitoring, community pharmacy, pharmacist talent management, etc.), and reviews. Index： China Pharmacy is one of the ‘Chinese Core Journals’, ‘China Science and Technology Core Journals’, ‘China Journal Square Double Effect Journal’, ‘RCCSE China Authoritative Academic Journals’, “China Academic Journal Impact Factor Annual Report”, and “National Open Platform for Science and Technology Journals”. From 2009 to 2014, it has been listed in ‘China Science Citation Database (CSCD) Source Journals’, ‘Chinese Biomedical Journal Literature Database (CMCC)’, ‘Chinese Biomedical Journal Literature Database’ and ‘Chinese Biomedical Journal Literature Database’. ‘Chinese Biomedical Journal Citation Database (CMCI), Chinese Journal Full Text Database (CJFD), Chinese Biomedical Literature Retrieval and Analysis System CD-ROM Database (CBMdisc). ‘‘World Impact Index of Scientific and Technical Journals (WJCI) Report (2021 Science and Technology Edition)’’ “Scopus” ’American Chemical Abstracts (CA) ‘‘Abstracts Journal (AJ), Russia’‘ “International Pharmaceutical Abstracts (IPA), USA”’ ‘WHO Western Pacific Region Index of Medicine (WPRIM) ‘‘Ullrich's Periodical Directory (UPD)’’, “Japan Science and Technology Agency Database (JST)” and other important domestic and international databases.