Progress in the treatment of Pneumocystis pneumonia

Tong-Zeng Li
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Abstract

Pneumocystis pneumonia (PCP) is a pulmonary disease that occurs frequently in immunocompromised and acquired human immunodeficiency virus infected patients.Severe patients can be life-threatening.Trimethoprim-sulfamethoxazole is the first choice for first-line treatment, but it has potential drug resistance.Most mild patients have good prognosis after using compound sulfamethoxazole and active treatment of primary diseases.However, for severe patients, due to lack of specific diagnostic methods in the early stage, the course of disease progresses rapidly, and glucocorticoid therapy can be combined to reduce the mortality of PCP.This article reviews the progress of treatment of PCP. Key words: Pneumonia; Homones; Sulfamethoxazole; Spores
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肺囊虫性肺炎的治疗进展
肺囊虫性肺炎(PCP)是一种常见于免疫功能低下和获得性人类免疫缺陷病毒感染患者的肺部疾病。严重的病人可能危及生命。甲氧苄啶-磺胺甲恶唑是一线治疗的首选药物,但有潜在的耐药性。多数轻症患者在应用复方磺胺甲恶唑并积极治疗原发疾病后预后良好。但对于重症患者,由于早期缺乏特异性的诊断方法,病程进展迅速,可联合糖皮质激素治疗,降低PCP的死亡率。本文就PCP的治疗进展作一综述。关键词:肺炎;性激素;磺胺甲恶唑;孢子
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