Machine Vision Based Method for Measuring Single-Cell Biophysical Properties Using Dielectrophoresis Mobility

Abstract

Measurement on single-cell biophysical properties is of great significance for cell sorting, cytopathology tracking, etc. Dielectrophoresis (DEP) based single-cell measurement has attracted increasingly interests because of its non-invasive, label-free, and easy integration with other functional structures. However, the measurement accuracy and efficiency of DEP-based method highly depends on cell motion tracking. Here, we propose a machine vision-based DEP motion tracking method to realize accurate and fast measurements on single-cell biophysical properties.