Frequency Spectrum Analysis of Signals Used in Transcorneal Electrical Stimulation

Jorge Santiago Amaya, José Antonio Mendoza Hernández, Félix Gil Carrasco, Jarumi Aguilar Guggembuhl, Claudio López García
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Abstract

The contribution of this research work focuses on understanding the biological behavior of time-varying electric fields, specifically in the eyeball, by proposing sensitive frequency ranges, specifically for primary open-angle glaucoma POAG and RP retinitis pigmentosa. These ranges were obtained from the analysis of the frequency spectrum of the signals used by other authors in transcorneal electrical stimulation TES therapies. This analysis was performed using an algorithm proposed in this work. The frequency spectra of the signals used in the TES were also compared with the frequency response of the cellular behavior evoked by genestein drug, in order to compare the frequency characteristics of the signals applied in the TES and the biological response of the drug. which causes the same effect in POAG.
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经角膜电刺激信号的频谱分析
本研究工作的贡献集中在了解时变电场的生物学行为,特别是在眼球中,通过提出敏感频率范围,特别是原发性开角型青光眼POAG和RP色素性视网膜炎。这些范围是从其他作者在经角膜电刺激TES疗法中使用的信号频谱分析中获得的。该分析是使用本工作中提出的算法进行的。将TES中使用的信号频谱与genestein药物引起的细胞行为的频率响应进行比较,以比较TES中使用的信号的频率特征与药物的生物反应。这在POAG中也会产生同样的效果。
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