Intrathecal Baclofen Pump Perioperative Management: Case Report and Literature Review

IF 0.1 Q4 ANESTHESIOLOGY Pediatric Anesthesia and Critical Care Journal Pub Date : 2022-01-01 DOI:10.26502/acc.046
Eduardo A Wilson-Manríquez, Mercedes Nicté López-Hernández, F. Lopez-jimenez, Rocío Torres-Méndez, Rafael Acuña-Prats
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Abstract

Background The use of intrathecal baclofen pumps (ITBP) has become increasingly common worldwide for the treatment of severe spasticity. Increased prevalence of patients using ITBPs makes encounters ever more common with surgical teams, these surgical interventions may be related to ITBP manipulation or completely unrelated to these devices. The anesthetist must be familiar with the normal functioning of ITBPs and be aware of baclofen pharmacokinetics in the cerebrospinal fluid, the occurrence of baclofen overdosing or withdrawal, and the potential pharmacological interactions between baclofen and drugs commonly used intraoperatively. We present the case of a successful management of a patient with chronic use of an ITBP which had to be suspended before undergoing a surgical procedure to perform intraoperative neuromonitoring to guide the surgical intervention. A good communication and organization of the multidisciplinary team improves the prognosis of the patient and reduces morbidity and mortality.
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鞘内巴氯芬泵围手术期管理:病例报告及文献复习
鞘内巴氯芬泵(ITBP)的使用在世界范围内越来越普遍,用于治疗严重痉挛。使用ITBP的患者越来越多,使得手术团队遇到的情况越来越普遍,这些手术干预可能与ITBP操作有关,也可能与这些设备完全无关。麻醉师必须熟悉itbp的正常功能,了解巴氯芬在脑脊液中的药代动力学,巴氯芬过量或停药的发生,以及巴氯芬与术中常用药物之间潜在的药理学相互作用。我们报告一例成功治疗的慢性ITBP患者,该患者在手术前必须暂停使用ITBP以进行术中神经监测以指导手术干预。多学科团队的良好沟通和组织可以改善患者的预后,降低发病率和死亡率。
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