Swotting effective hypertension therapy: Ramipril versus telmisartan

R. Das
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Abstract

One of the most important, globally controllable risk factors for cardiovascular diseases and early mortality is hypertension. Angiotensinconverting enzyme inhibitors and angiotensin receptor blockers, both of which inhibit the renin-angiotensin system, are becoming more common as initial treatments for the management of hypertension patients with which ramipril and telmisartan being the most frequently used. Telmisartan has the highest affinity for the AT1 receptor of all the ARBs.Ramipril and telmisartan both are found to provide a variety of therapeutic advantages. In this study, a detailed comparative analysis has been done between ramipril and telmisartan regarding their efficacy, safety, monotherapy as well as combination therapy outcome and measures to be taken while considering both drugs. This study focused on which one is more successful in treating hypertension individuals, while also having a superior safety profile and combining the two medications which one is linked to more side effects, additional benefits, or other important information to eliminate the hazards connected to blood pressure increase while minimizing negative effects on quality of life.
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有效的高血压治疗:雷米普利与替米沙坦
高血压是心血管疾病和早期死亡最重要的、全球可控的危险因素之一。血管紧张素转换酶抑制剂和血管紧张素受体阻滞剂,两者都抑制肾素-血管紧张素系统,作为高血压患者管理的初始治疗越来越普遍,其中雷米普利和替米沙坦是最常用的。替米沙坦对所有arb的AT1受体具有最高的亲和力。雷米普利和替米沙坦都具有多种治疗优势。在本研究中,我们对雷米普利和替米沙坦的疗效、安全性、单药治疗和联合治疗的结果以及考虑两种药物时应采取的措施进行了详细的比较分析。这项研究的重点是哪一种药物在治疗高血压患者方面更成功,同时也有更好的安全性,并将两种药物结合起来,哪一种药物有更多的副作用,额外的好处,或其他重要信息,以消除与血压升高有关的危害,同时最大限度地减少对生活质量的负面影响。
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