Existence of immunological memory response in true sero-negative individuals post COVID-19 molecular diagnosis.

IF 4.2 2区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY Chinese Physics Letters Pub Date : 2022-03-10 DOI:10.1093/cid/ciac196
Yaniv Lustig, Ella Mendelson, Michal Mandelboim, Asaf Biber, Einav G Levin, Carmit Cohen, Gili Regev-Yochay, Eli Schwartz
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引用次数: 0

Abstract

Approximately 1-8% of individuals do not develop antibodies following SARS-CoV-2 infection (sero-negatives). One BNT162b2 dose resulted in potent humoral response in 14 sero-negatives and 15 sero-positives, significantly higher than the response of 15 naïve-individuals, to two doses suggesting that COVID-19 provoked a memory response in individuals without detectable antibodies.

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COVID-19 分子诊断后血清真正阴性的个体存在免疫记忆反应。
大约有 1-8%的人在感染 SARS-CoV-2 后不会产生抗体(血清阴性者)。一个剂量的 BNT162b2 可使 14 个血清阴性者和 15 个血清阳性者产生强烈的体液反应,明显高于 15 个天真个体对两个剂量的反应,这表明 COVID-19 在没有检测到抗体的个体中激起了记忆反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Chinese Physics Letters
Chinese Physics Letters 物理-物理:综合
CiteScore
5.90
自引率
8.60%
发文量
13238
审稿时长
4 months
期刊介绍: Chinese Physics Letters provides rapid publication of short reports and important research in all fields of physics and is published by the Chinese Physical Society and hosted online by IOP Publishing.
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