A REVIEW ON IMMUNOMODULATORY ACTIVITY OF HERBAL DRUGS IN INDIAN TRADITIONAL SYSTEMS OF MEDICINE

YMER Digital Pub Date : 2022-08-08 DOI:10.37896/ymer21.08/21
Mansi Aggarwal
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Abstract

Immunomodulators play a key role in immunity of each animal in this world. Almost all animals have their own system to produce different immunomodulators at different time. Herbal medicines constitute a major component in all traditional and alternative systems of medicines like siddha, ayurveda, homeopathy, naturopathy, yogic science and native american medicines. This review emphasizes on twenty-five herbal drugs including Withania somnifera, Morus Alba Linn, Acacia catechu, Achillea wilhelmsii, L. Panax ginseng, Garlic (Allium Sativum), Terminalia Arjuna, Rhus toxicodendron and many more for their Immunomodulatory potential. In addition, many of the immune-boosting and health promoting drugs are available in the market in various dosage forms like in the form of tablets, capsules, candies, juices, kadha, tea, chyawanprash, are also mentioned. Increase in the levels of total leucocytes count (TLC), Differential leucocytes count (DLC), foot paw volume, phagocytic index was observed in delayed type hypersensitivity (DTH) response, Neutrophil adhesion test, Acute paw anaphylaxis, phagocytosis, etc, are in vivo and in vitro biological screening methods used for the immunomodulatory activity. [2] Accordingly, this review provides numerous evidences which indicates that these medicinal drugs can be used for treating and boosting immune system and related complications. Keywords: Immune framework, Immune rule, Plant drugs, immunity boosters, marketed preparations.
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印度传统医学体系中草药免疫调节活性的研究进展
免疫调节剂在世界上每一种动物的免疫中都起着关键作用。几乎所有的动物都有自己的系统,在不同的时间产生不同的免疫调节剂。草药是所有传统和替代药物系统的主要组成部分,如悉达法、阿育吠陀、顺势疗法、自然疗法、瑜伽科学和美洲土著药物。本文重点介绍了25种具有免疫调节作用的中药,包括苦参、桑、儿茶、阿喀琉叶、人参、大蒜、阿朱那、毒竹等。此外,市场上有许多增强免疫和促进健康的药物,其剂型多种多样,如片剂、胶囊、糖果、果汁、卡达、茶、chyawanprash等。在延迟型超敏反应(DTH)、中性粒细胞粘附试验、急性足跖过敏反应、吞噬等方面观察到总白细胞计数(TLC)、差异白细胞计数(DLC)、足跖体积、吞噬指数等水平的增加,是体内体外生物筛选方法用于免疫调节活性的方法。因此,本综述提供了大量证据,表明这些药物可用于治疗和增强免疫系统及其相关并发症。关键词:免疫框架,免疫规律,植物药,免疫增强剂,上市制剂
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