V. Skripova, L. Bulatova, D. Savenkova, A. K. Nurgalieva, R. Vlasenkova, D. Reshetnikova, A. Timonina, M. Bogdanov
{"title":"MOLECULAR MARKERS FOR CANCER DIAGNOSIS AND THERAPY","authors":"V. Skripova, L. Bulatova, D. Savenkova, A. K. Nurgalieva, R. Vlasenkova, D. Reshetnikova, A. Timonina, M. Bogdanov","doi":"10.37747/2312-640x-2021-19-142-144","DOIUrl":null,"url":null,"abstract":"Using CRISPR/Cas9 and SEREX technologies we have identified and characterized more than two hundred potential molecular markers of oncological diseases. It was shown that the sodium-dependent phosphate transporter NaPi2b is a unique target for the development of antitumor targeted drugs due to its localization and tumor-specific epitope.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"25 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"http://eng.biomos.ru/conference/articles.htm","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37747/2312-640x-2021-19-142-144","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Using CRISPR/Cas9 and SEREX technologies we have identified and characterized more than two hundred potential molecular markers of oncological diseases. It was shown that the sodium-dependent phosphate transporter NaPi2b is a unique target for the development of antitumor targeted drugs due to its localization and tumor-specific epitope.