{"title":"Predicting a Power Law Between Elastic Modulus and Porosity in Cortical Bone: A Micromechanics Model","authors":"X. N. Dong, X. Guo","doi":"10.1115/imece2001/bed-23032","DOIUrl":null,"url":null,"abstract":"\n Age-related changes in microstructure and composition of bone tissue are becoming increasing important as people continue to live longer. The cortical porosity increases with age in both men and women [1]. Age related increases in Haversian canal size and Haversian canal number contribute to the increasing porosity of cortical bone for the elderly men and women [2, 3]. The number of osteoclastic resorption space is also greater in the old men than in the young men [3]. The increased porosity and the higher prevalence of giant Haverian canals have a markedly negative influence on the ability of the cortical shell to withstand mechanical loads associated with a fall [4].","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"11 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1115/imece2001/bed-23032","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Age-related changes in microstructure and composition of bone tissue are becoming increasing important as people continue to live longer. The cortical porosity increases with age in both men and women [1]. Age related increases in Haversian canal size and Haversian canal number contribute to the increasing porosity of cortical bone for the elderly men and women [2, 3]. The number of osteoclastic resorption space is also greater in the old men than in the young men [3]. The increased porosity and the higher prevalence of giant Haverian canals have a markedly negative influence on the ability of the cortical shell to withstand mechanical loads associated with a fall [4].