Aqueous humor and iris mechanics in synechial closure in primary angle-closure glaucoma

E. C. Huang, J. Heys, V. Barocas
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Abstract

Primary angle-closure glaucoma features a narrow anterior chamber angle in which the anteriorly positioned iris blocks aqueous humor outflow through the trabecular meshwork, subsequently increasing the intraocular pressure. A mathematical model is used to investigate the aqueous humor-iris interaction in synechial angle closure. The model predicted increased intraocular pressure as the anterior chamber angle decreased and a plateau iris configuration in synechial angle closure - consistent with clinical observations.
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原发性闭角型青光眼的虹膜力学与房水力学
原发性闭角型青光眼的特点是前房角狭窄,位于前侧的虹膜阻断房水通过小梁网流出,导致眼压升高。采用数学模型研究了体液-虹膜在协同角闭合过程中的相互作用。该模型预测,随着前房角的减小和虹膜平台的闭合,眼压升高,这与临床观察一致。
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