Factors affecting compliance for iron chelating agents in thalassemic patients in Basrah province, Iraq

S. Jabur, Hadeel Rashid Abdul Hameed
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Abstract

the remaining 32% of patients were live in urban areas. In the current study, the number of patients were taking oral chelating therapy (Exjad) was 116 patients (80%), while the number of patients taking injectable chelating therapy (Desferoxamine) was 29 patients (20%), (Figure 2). In the current study, we found that 42 patients (29%) had very accepted to their treatment and they are on regular way of treatment, 34 patients (23.4%) had not accept their treatment and they are on irregular AbstractObjectives: To assess factors that affect patient’s compliance for various type of chelating agents for thalassemic patients using direct questionnaires throughout 5 months period. Methods: A prospective screening study done on patients with diagnosed transfusion-dependent β-thalassemia treated on different types of iron chelating agents. Thalassemia unit in AL-Zahraa teaching hospital. Evaluation of patient’s preferability for chelation therapy, predictive values and reliability. Results: In the current study, we found that 88 patients (60%) had accept the treatment in different degrees while the remaining number of patients (57 patients, 39.3%) had not accept their treatment. Conclusion: In β-thalassemia compliance, monitoring using several methods is crucial as non-compliance is common and is associated with decreased survival. In addition, to have a good ideas about maintaining a reliable time for patient to continue on his chelating therapy.
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影响伊拉克巴士拉省地中海贫血患者铁螯合剂依从性的因素
其余32%的患者生活在城市地区。在本研究中,口服螯合治疗(Exjad)患者116例(80%),注射螯合治疗(去铁氨明)患者29例(20%)(图2)。在本研究中,我们发现42例(29%)患者对其治疗非常接受,并按常规治疗,34例(23.4%)患者不接受治疗,不定期治疗。通过5个月的直接问卷调查,评估影响地中海贫血患者对各类螯合剂依从性的因素。方法:对诊断为输血依赖性β-地中海贫血的患者进行不同类型铁螯合剂治疗的前瞻性筛选研究。扎赫拉教学医院的地中海贫血科。评估患者对螯合治疗的偏好、预测价值和可靠性。结果:在本研究中,我们发现88例(60%)患者不同程度地接受了治疗,其余57例(39.3%)患者不接受治疗。结论:在β-地中海贫血依从性中,使用多种方法进行监测是至关重要的,因为不依从性是常见的,并且与生存率降低有关。此外,要有一个好的想法,保持一个可靠的时间,让病人继续他的螯合治疗。
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审稿时长
12 weeks
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