{"title":"The potential mechanism of ubiquitin-proteasome system in non-small cell lung cancer","authors":"Yuxiu Wang","doi":"10.3760/CMA.J.ISSN.1673-436X.2020.04.008","DOIUrl":null,"url":null,"abstract":"The ubiquitin-proteinasome system (UPS) is a complex control system responsible for the degradation of 80%-90% of proteins and is the key to regulating cellular function and maintaining protein homology.Studies have shown that it plays an important role in the development of a variety of tumors.Therefore, the component of UPS has attracted extensive attention as a potential target for the diagnosis and treatment of lung cancer in recent years.This article reviews the research status of UPS in non-small cell lung cancer and its potential mechanism in the development of non-small cell lung cancer. \n \n \nKey words: \nCarcinoma, non-small-cell lung; Ubquitin-proteinasome system; Mechanism","PeriodicalId":10004,"journal":{"name":"Chinese Journal of Asthma","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Journal of Asthma","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-436X.2020.04.008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The ubiquitin-proteinasome system (UPS) is a complex control system responsible for the degradation of 80%-90% of proteins and is the key to regulating cellular function and maintaining protein homology.Studies have shown that it plays an important role in the development of a variety of tumors.Therefore, the component of UPS has attracted extensive attention as a potential target for the diagnosis and treatment of lung cancer in recent years.This article reviews the research status of UPS in non-small cell lung cancer and its potential mechanism in the development of non-small cell lung cancer.
Key words:
Carcinoma, non-small-cell lung; Ubquitin-proteinasome system; Mechanism
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