Multiphysics Modeling of Magnetic Scaffolds for Biomedical Applications

M. B. Lodi, A. Fanti
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Abstract

Magneto-responsive biomaterials can play a key role in several biomedical applications, from therapeutic to diagnostic. Despite the several efforts for synthesizing and characterizing bioceramics doped with magnetic ions or polymers loaded with magnetic nanoparticles, there is lack of mathematical and numerical models capable of filling the gap between nanomaterial science and engineering. This work reviews and propose numerical, multiphysics models for studying the use of magnetic scaffolds for the hyperthermia treatment of bone tumors and for magnetically targeted drug delivery.
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生物医学磁性支架的多物理场建模
磁响应生物材料可以在几个生物医学应用中发挥关键作用,从治疗到诊断。尽管在合成和表征掺杂磁性离子的生物陶瓷或装载磁性纳米粒子的聚合物方面做出了一些努力,但缺乏能够填补纳米材料科学与工程之间空白的数学和数值模型。本研究综述并提出了用于研究磁性支架在骨肿瘤热疗和磁性靶向药物递送中的应用的数值多物理场模型。
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