An improved rank based disease prediction using web navigation patterns on bio-medical databases

P. Dhanalakshmi , K. Ramani , B. Eswara Reddy
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引用次数: 6

Abstract

Applying machine learning techniques to on-line biomedical databases is a challenging task, as this data is collected from large number of sources and it is multi-dimensional. Also retrieval of relevant document from large repository such as gene document takes more processing time and an increased false positive rate. Generally, the extraction of biomedical document is based on the stream of prior observations of gene parameters taken at different time periods. Traditional web usage models such as Markov, Bayesian and Clustering models are sensitive to analyze the user navigation patterns and session identification in online biomedical database. Moreover, most of the document ranking models on biomedical database are sensitive to sparsity and outliers. In this paper, a novel user recommendation system was implemented to predict the top ranked biomedical documents using the disease type, gene entities and user navigation patterns. In this recommendation system, dynamic session identification, dynamic user identification and document ranking techniques were used to extract the highly relevant disease documents on the online PubMed repository. To verify the performance of the proposed model, the true positive rate and runtime of the model was compared with that of traditional static models such as Bayesian and Fuzzy rank. Experimental results show that the performance of the proposed ranking model is better than the traditional models.

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基于生物医学数据库web导航模式的疾病预测改进排名
将机器学习技术应用于在线生物医学数据库是一项具有挑战性的任务,因为这些数据是从大量来源收集的,并且是多维的。此外,从大型存储库中检索相关文档(如基因文档)需要更多的处理时间和更高的假阳性率。一般来说,生物医学文献的提取是基于在不同时期对基因参数的先前观察流。传统的马尔可夫模型、贝叶斯模型和聚类模型对在线生物医学数据库中的用户导航模式分析和会话识别比较敏感。此外,大多数生物医学数据库的文献排序模型对稀疏度和离群值敏感。本文利用疾病类型、基因实体和用户导航模式,实现了一种新的用户推荐系统来预测排名靠前的生物医学文献。该推荐系统采用动态会话识别、动态用户识别和文档排序技术,从在线PubMed知识库中提取相关度高的疾病文档。为了验证该模型的性能,将该模型的真阳性率和运行时间与传统的静态模型(如贝叶斯和模糊秩)进行了比较。实验结果表明,该排序模型的性能优于传统的排序模型。
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