Protective Effects of Silver Nanoparticles of Moringa Oleifera Leaves against Acrylamide-Induced Blood Toxicity in Rats .

Abstract

The present study aimed to indicate the harmful effects of Acrylamide (ACR) on blood cell of rats and the protective role of silver nanoparticles (Ag-NPs) derived from Moringa oleifera ( M .oleifera ) leaves against this effects. Ag-NPs were produced and subsequently examined using Transmission Electronic Microscope and Dynamic Light scattering measurements. Twenty adult male albino rats were randomly divided into four groups (five per each):Control group; ACR group (50 mg/kg b.wt, in drinking water); MO-NPsACRS group (50 mg/kg b.wt, orally at the same time of each treatment) and Protective group, (MO-NPs/ACR group), MO-NPs for 3 weeks (50 mg/kg b.wt, orally) then ACR for 3 weeks (50 mg/kg b.wt). At the end of the experimental period, blood samples were collected in clean tubes containing anticoagulant for blood cells count.