AI ON A CHIP FOR IDENTIFYING MICROALGAL CELLS WITH HIGH HEAVY METAL REMOVAL EFFICIENCY

Muzhen Xu, J. Harmon, T. Hasunuma, A. Isozaki, K. Goda
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引用次数: 1

Abstract

Microalgae-based methods used in heavy metal (HM)-polluted wastewater treatment have attracted increasing attention in recent decades, due to their eco-friendliness, profitability, and sustainability. Unfortunately, their low HM removal efficiency hinders them from practical use. In this work, we report an AI-on-a-chip method, a combination of AI and lab-on-a-chip technology, for identifying Euglena gracilis (a microalgal species) cells with high HM removal efficiency through a morphological meta-feature. In the near future, the implementation of the morphological meta-feature in a high-throughput cell sorting process will pave the way for realizing directed-evolution-based development of microalgae with extremely high HM removal efficiency for practical wastewater treatment worldwide.
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一种用于鉴定具有高重金属去除效率的微藻细胞的芯片
近几十年来,基于微藻的重金属污染废水处理方法因其环保性、盈利性和可持续性而受到越来越多的关注。不幸的是,它们的低HM去除效率阻碍了它们的实际应用。在这项工作中,我们报告了一种AI-on-a-chip方法,该方法结合了AI和lab-on-a-chip技术,通过形态学元特征识别具有高HM去除效率的Euglena gracilis(一种微藻)细胞。在不久的将来,形态学元特征在高通量细胞分选过程中的实现将为实现定向进化开发具有极高HM去除效率的微藻铺平道路,用于世界范围内的实际废水处理。
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