{"title":"Lipid Microspheres (Lipid Emulsions)","authors":"F. Ishii","doi":"10.5650/JOS1996.49.1141","DOIUrl":null,"url":null,"abstract":"Lipid microspheres (Lipid emulsions) should prove useful colloidal drug carriers in various therapeutic applications and as parenteral delivery systems owing to their ability to incorporate lipid-soluble drugs in dispersing phases. Lipid microspheres are o/w emulsions similar to commercially available fat emulsions. The oil droplets in the dispersing systems function as drug containing reservoirs. Surface modification of oil particles in emulsions adjust drug release rate and affinity for target sites. Recent advances in the development of lipid microspheres are discussed and comparison is made with conventional preparations.","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2000-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Japan Oil Chemists Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5650/JOS1996.49.1141","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Lipid microspheres (Lipid emulsions) should prove useful colloidal drug carriers in various therapeutic applications and as parenteral delivery systems owing to their ability to incorporate lipid-soluble drugs in dispersing phases. Lipid microspheres are o/w emulsions similar to commercially available fat emulsions. The oil droplets in the dispersing systems function as drug containing reservoirs. Surface modification of oil particles in emulsions adjust drug release rate and affinity for target sites. Recent advances in the development of lipid microspheres are discussed and comparison is made with conventional preparations.
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