Literature review: pharmacological effects of vitamin D in the body to enhance athletic performance

N. G. Sarkisyan, E. Gaisina, M. N. Dobrinskaya, Milana A. Shmakova, P. Astryukhina, Artyom S. Goskov
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Abstract

Studies (domestic and foreign) on the effect of vitamin D on muscle strength, muscle recovery rate, maximum oxygen consumption and prevention of skeletal muscle injury reduction have been analyzed. At the same time it was found that athletes are susceptible to hypovitaminosis no less often than standard population groups due to higher physical loads. It is unequivocally possible to say that vitamin D supplementation improves the physical fitness of athletes and can correct their condition in the autumn-spring period. Objective: an analysis of literature data based on the significance of the pharmacological effects of vitamin D in the functioning of the musculoskeletal system of the body and its role of improving athletic performance. Material and methods. The Pubmed/MEDLINE digital scientific library was chosen as the main source of information. Additionally, the search included the repositories of open access preprints from eLIBRARY.RU for 2016-2022. Key words for the search query were "vitamin D," "calcitriol," "sports," and "athletes." The results of the study are reported taking into account PRISMA recommendations. Results. Duration and quality of insolation directly affect vitamin D levels. Additional sun exposure combined with the use of vitamin D preparations contributes to the elimination of vitamin D deficiency. Vitamin D deficiency can lead to decreased intranuclear VDR concentrations and decreased VDR gene expression, which contributes to myopathy following atrophy of type IIA muscle fibers. Additional enrichment of special electrolyte solutions with water-soluble vitamin D is reasonable. Conclusion. Continuous monitoring of the concentration of 25(OH)D in the blood serum of athletes is an integral part in the development of recommendations for improving health and sports performance in training and competitive regimes. Individual correction of vitamin D should be carried out in accordance with changes in its level in each athlete.
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文献综述:维生素D在体内具有提高运动成绩的药理作用
国内外有关维生素D对肌力、肌肉恢复速度、最大耗氧量和预防骨骼肌损伤减少的研究进行了分析。同时发现,由于较高的体力负荷,运动员易患维生素缺乏症的几率并不低于标准人群。可以明确地说,补充维生素D可以改善运动员的身体素质,并可以纠正他们在秋春季节的状况。目的:根据文献资料分析维生素D在人体肌肉骨骼系统功能中的药理作用及其对提高运动成绩的作用的意义。材料和方法。选择Pubmed/MEDLINE数字科学图书馆作为主要信息来源。此外,搜索还包括来自eLIBRARY的开放获取预印本存储库。2016-2022年俄服。搜索查询的关键词是“维生素D”、“骨化三醇”、“运动”和“运动员”。报告的研究结果考虑了PRISMA的建议。结果。日照的持续时间和质量直接影响维生素D水平。额外的阳光照射加上维生素D制剂的使用有助于消除维生素D缺乏症。维生素D缺乏可导致核内VDR浓度降低和VDR基因表达降低,从而导致IIA型肌纤维萎缩后的肌病。在特殊电解质溶液中添加水溶性维生素D是合理的。结论。持续监测运动员血清中25(OH)D的浓度是在训练和比赛制度中制定改善健康和运动表现建议的一个组成部分。应根据每个运动员体内维生素D水平的变化对维生素D进行个人校正。
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