The study of the antioxidant activity of the antiulcerous plant composition and its components

E. V. Ferubko, V. N. Zelenkov, Tamara D. Dergaeva, A. Lapin
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Abstract

At present, the expansion of research to find sources for obtaining new effective and safe medicines of plant origin, including those used in gastroenterological practice, is a pressing task of medical science, considering that the range of medicinal plant drugs used in practical health care is more than 40%. The article presents the results of biochemical study of total antioxidant activity of anti-ulcer collection of plant origin and its individual components. We show that it consists of the leaves of the planter large (Plantago major L.), grass of a sushchenitsa uliginose (Gnaphalium uliginosum L.), rhizomes and roots of the devisil high (Inula helenium L.), flowers of the chamomile pharmacy (Matricaria chamomilla L.), the roots of licorice naked (Glycyrrhiza glabra L.), grass of bird's mountain (Polygonum aviculare L.), leaves of the nettle (Urtica dioica L.), fruits of a mountain ash ordinary (Sorbus aucuparia L.) and its individual components have pronounced antioxidant activity. The greatest activity was found in the roots of licorice naked, grass of bird 's mountain and flowers of chamomile pharmacy. Total antioxidant activity of water extraction of collection recovery at 6.34% from exceeded the calculated value obtained by summing the activities of the individual components of the collection, which indicates the presence of synergy in their action, which may be of importance for use in the treatment and prevention of diseases in gastroenterological practice. The detected increase in the antioxidant activity of the new collection compared to the effects of its individual components allows it to be considered as a promising dosage form for the treatment and prevention of gastroenterological diseases.
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抗溃疡植物组合物及其组分抗氧化活性的研究
目前,考虑到实际卫生保健中使用的药用植物药物的范围超过40%,扩大研究范围以获得新的有效和安全的植物药物,包括用于胃肠病学实践的植物药物,是医学科学的一项紧迫任务。本文介绍了植物源性抗溃疡提取物及其单个成分的总抗氧化活性的生化研究结果。我们发现它由大植物(Plantago major L.)的叶子、一种植物(Gnaphalium uliginosum L.)的草、一种植物(Inula helenium L.)的根茎和根、洋甘菊的花(Matricaria chamomilla L.)、甘草的根(glycyrhiza glabra L.)、鸟山草(Polygonum aviculare L.)、荨麻的叶子(Urtica dioica L.)组成。山灰(Sorbus aucuparia L.)的果实及其个别成分具有明显的抗氧化活性。甘草根、鸟山草和洋甘菊花活性最强。收集回收的水提物的总抗氧化活性为6.34%,超过了收集中单个组分活性总和的计算值,这表明它们的作用存在协同作用,这可能在胃肠病学实践中用于疾病的治疗和预防中具有重要意义。与单个成分的效果相比,新收集的抗氧化活性检测到的增加使其被认为是治疗和预防胃肠疾病的有希望的剂型。
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