Analytical review of prescription of prophylactic antibiotic in urologic procedures

Abstract

Introduction: Prophylactic antibiotics are used before or at the beginning of diagnostic or therapeutic intervention to reduce post-intervention infections. Objectives: The aim of this study was to compare the administration of prophylactic antibiotics in urological procedures of Imam Reza hospital in Tabriz with the standard protocol. Patients and Methods: This cross-sectional study was performed on common urological cases including 400 patients who undergo open or endoscopic surgery who received antibiotic prophylaxis before surgery to prevent urinary tract infections. Results: The mean age of the patients was 49.59 ± 17.60 years; 51.5% of the patients were female. The most common cystoscopy procedure was performed with a frequency of 27.25% and the most common antibiotic used was cefazolin with a frequency of 34.25%. It was observed that there was a discrepancy between the type of antibiotic in 4.4% and a discrepancy between the dose of antibiotics used and the standard guideline in 5.5%. The mean duration of drug administration in the studied patients was 3.28±1.59 days with a mean of three days. Regarding duration of antibiotic use, in 26% of cases was contrary to the standard guideline. Additionally, in 11.25% of cases, the continuation of prophylactic antibiotics in the studied patients was contrary to the standard guideline. Conclusion: In the present study, the time of administration of prophylactic antibiotics before urological surgeries was the most consistent with the standard guideline. In addition, most cases of discrepancy between dose and type of antibiotic were related to stent replacement and cystoscopy.