Correlation between fine needle aspiration and intraoperative frozen section findings for thyroid patients; a single center study

A. Baradaran, M. Derakhshan, Negin Ghanbari
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Abstract

Introduction: Thyroid nodules are one of the most common diseases. Objectives: The aim of this study was to evaluate the correlation between fine needle aspiration (FNA) and intraoperative frozen section findings for thyroid disease patients. Patients and Methods: In this study, the FNA and intraoperative frozen section findings of 143 patients who were admitted to an educational hospital, Isfahan, Iran were collected and classified using these diagnostic methods during 2015. To find the correlation between FNA and intraoperative frozen section findings, statistical analysis was conducted using SPSS software version 16.0 (Chicago, IL). Results: Sensitivity and specificity of the positive FNA findings were 71% and 86.8%, respectively (P<0.001). The maximum concordance between FNA and intraoperative frozen section for papillary thyroid cancer was seen (P<0.001). Conclusion: In this study, a significant association between FNA and intraoperative frozen section of thyroid cancers, among our patients, however this finding requires further investigation by larger studies.
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甲状腺细针穿刺与术中冰冻切片的相关性研究单中心研究
简介:甲状腺结节是最常见的疾病之一。目的:本研究的目的是评估细针穿刺(FNA)与甲状腺疾病患者术中冰冻切片结果的相关性。患者和方法:本研究收集2015年伊朗伊斯法罕一家教育医院收治的143例患者的FNA和术中冷冻切片结果,并采用这些诊断方法进行分类。为了发现FNA与术中冰冻切片结果的相关性,使用SPSS软件16.0 (Chicago, IL)进行统计分析。结果:FNA阳性诊断的敏感性为71%,特异性为86.8% (P<0.001)。FNA与术中冰冻切片对甲状腺乳头状癌的一致性最大(P<0.001)。结论:在本研究中,FNA与术中甲状腺癌冷冻切片之间存在显著相关性,但这一发现需要进一步进行更大规模的研究。
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