Evidence-based nutritional patterns for type 2 diabetes prevention and treatment

Q3 Medicine Voprosy Detskoi Dietologii Pub Date : 2022-01-01 DOI:10.20953/2224-5448-2022-4-11-22

K. Sharafetdinov, O. A. Plotnikova, R. I. Alekseeva, V. V. Pilipenko, V. Alekseev

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Abstract

Type 2 diabetes mellitus (T2DM) is one of the most common carbohydrate metabolism disorders worldwide. Despite individual predisposition to T2DM due to non-modifiable risk factors (ethnicity and family history/genetic predisposition), epidemiological evidence suggests that many cases of T2DM can be prevented by modifying underlying risk factors (obesity, low physical activity, unhealthy diet). In a state of overnutrition leading to hyperglycemia and dyslipidemia, insulin resistance, and chronic inflammation, pancreatic β-cells are exposed to toxic effects, and conditions of inflammation and metabolic/oxidative stress result in obesity, insulin resistance, and the development of T2DM. The global impact of T2DM on the health care system requires early detection of carbohydrate metabolism disorders and preventive measures including lifestyle changes and dietary recommendations. This review considers the effect of different patterns (models) of nutritional intervention as an effective, safe, and low-cost method for the prevention and treatment of T2DM. Key words: therapeutic nutrition, nutritional patterns, type 2 diabetes mellitus, nutritional intervention

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2型糖尿病预防和治疗的循证营养模式

2型糖尿病(T2DM)是世界上最常见的碳水化合物代谢紊乱之一。尽管个体易患2型糖尿病是由于不可改变的危险因素(种族和家族史/遗传易感性)，但流行病学证据表明，许多2型糖尿病病例可以通过改变潜在的危险因素(肥胖、低体力活动、不健康饮食)来预防。在营养过剩导致高血糖和血脂异常、胰岛素抵抗和慢性炎症的状态下，胰腺β细胞暴露于毒性作用，炎症和代谢/氧化应激条件导致肥胖、胰岛素抵抗和T2DM的发展。T2DM对卫生保健系统的全球影响需要早期发现碳水化合物代谢紊乱，并采取包括改变生活方式和饮食建议在内的预防措施。这篇综述考虑了不同模式(模式)的营养干预作为一种有效、安全、低成本的预防和治疗2型糖尿病的方法的效果。关键词:治疗性营养，营养模式，2型糖尿病，营养干预

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来源期刊

Voprosy Detskoi Dietologii Medicine-Pediatrics, Perinatology and Child Health

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： The scientific journal Voprosy Detskoi Dietologii is included in the Scopus database. Publisher country is RU. The main subject areas of published articles are Food Science, Pediatrics, Perinatology, and Child Health, Nutrition and Dietetics, Клиническая медицина.