The risks of perinatal HIV/HCV co-infection and the evolution of treatment tactics of the disease in children (clinical case)

A. A. Khamatova, T. A. Chebotareva, J. F. Vlatskaya
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Abstract

HIV infection and HCV infection are still serious and widespread infections that lead to high morbidity and mortality of the population worldwide.The aim is to assess the risks of perinatal transmission of HIV/HCV co-infection and the choice of modern treatment tactics in children.Аnalyzed data in foreign and domestic literature. A clinical case of perinatal transmission of HIV/HCV co-infection is described.Results. Тhe features of perinatal transmission of infection depending on its variants (mono-HIV infection, hepatitis C and co-infection with HIV/HCV) and risk factors are shown. A clinical example demonstrates the implementation of perinatal transmission of HIV/HCV co-infection in the presence of major risk factors. The improvement of therapeutic tactics in a child with co-infection is shown.Conclusion: in the described clinical case, numerous risk factors for perinatal transmission of HIV/HCV co-infection are demonstrated, the presence of which led to the realization of co-infection in a child. The effectiveness of modern tactics for the treatment of HIV infection and chronic viral hepatitis C has been demonstrated.
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儿童围产期HIV/HCV合并感染的风险及治疗策略的演变(临床病例)
艾滋病毒感染和丙型肝炎病毒感染仍然是严重和广泛的感染,导致全世界人口的高发病率和死亡率。目的是评估艾滋病毒/丙型肝炎病毒合并感染的围产期传播风险和儿童现代治疗策略的选择。Аnalyzed数据来源于国内外文献。本文报道1例围产期HIV/HCV合并感染的临床病例。Тhe根据其变体(单HIV感染、丙型肝炎和HIV/HCV合并感染)和危险因素,显示了围产期感染传播的特征。一个临床实例表明,在存在主要危险因素的情况下,实施艾滋病毒/丙型肝炎病毒合并感染的围产期传播。显示了儿童合并感染的治疗策略的改进。结论:在所描述的临床病例中,证明了围产期传播HIV/HCV合并感染的许多危险因素,这些因素的存在导致了儿童合并感染的实现。现代战术的有效性治疗艾滋病毒感染和慢性病毒性丙型肝炎已被证明。
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