Sequential parylene lift-off process for selective patterning of biological materials

K. Kuribayashi, Yuichi Hiratsuka, T. Yamamura, Shoji Takeuchi
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引用次数: 6

Abstract

This paper describes a method of selective patterning of various types of biological materials with parylene lift-off process. Multiple parylene thin sheets with a microhole array were formed on a glass substrate, and were then sequentially peeled off during the pattering process. Using this method we have achieved high density patterning of different kinds of beads, lipids and proteins on the same substrate, respectively. We have also patterned proteins on a parylene sheet, and rolled up the sheet to a cylindrical structure as a demonstration of 3D protein chips.
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生物材料选择性图像化的序贯聚对二甲苯分离工艺
本文介绍了一种利用聚对二甲苯脱模工艺对各类生物材料进行选择性图案化的方法。在玻璃基板上形成具有微孔阵列的多个聚对二甲苯薄片,然后在图案化过程中依次剥离。利用这种方法,我们分别在相同的底物上实现了不同种类的珠子、脂质和蛋白质的高密度图案。我们还在聚对二甲苯薄片上绘制了蛋白质的图案,并将薄片卷成圆柱形结构,作为3D蛋白质芯片的演示。
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