A review on emerging herbal nanotechnology for skin cancer

Teena Patidar, S. Ramteke
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Abstract

Many phytochemicals such as tannins, terpenoids and flavonoids are hydrophilic in nature, but have low absorption, because they are unable to cross lipid membranes of cells. It has been proposed to combine phytomedicine to nanotechnology, because nanocarrier can deliver active phytochemical during entire treatment period, directing it to the desired site of action. The main aim of this work is to review Phytochemicals which possess promising anti-carcinogenic capabilities in a variety of skin cancer cell lines, animal models and their mechanism of action. The commercial formulations for skin cancer prevention and therapy that are now on the market that is derived from plants are also covered in this review. This paper focused on the recent assessment of the biological obstacles to topical applications of phytoconstituents and also focuses on review of the enormous potential for bioactive phytochemical distribution via developing nanotechnology.
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新兴的草药纳米技术治疗皮肤癌的综述
许多植物化学物质,如单宁、萜类和类黄酮,在本质上是亲水的,但吸收低,因为它们不能穿过细胞的脂质膜。由于纳米载体可以在整个治疗过程中传递活性的植物化学物质,并将其引导到所需的作用部位,因此有人提出将植物医学与纳米技术相结合。本文综述了在多种皮肤癌细胞系、动物模型中具有抗癌作用的植物化学物质及其作用机制。目前市场上用于预防和治疗皮肤癌的商业配方也包括从植物中提取的成分。本文重点介绍了植物成分局部应用的生物学障碍的最新评估,并着重介绍了通过发展纳米技术在生物活性植物化学分布方面的巨大潜力。
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