S. Jacques, P. Bargo, T. Goodell, R. Sleven, G. Kovall, G. Blair
{"title":"Variability of tissue optical properties in cancer patients receiving photodynamic therapy","authors":"S. Jacques, P. Bargo, T. Goodell, R. Sleven, G. Kovall, G. Blair","doi":"10.1109/IEMBS.2002.1053283","DOIUrl":null,"url":null,"abstract":"Photodynamic Therapy (PDT) uses light to activate photosensitive drug to yield oxidative injury to targeted tissues such as cancer. The ability of treatment light to penetrate a tissue and activate the drug that has accumulated in a target tissue depends on the tissue optical properties, especially the blood perfusion. An endoscopic spectroscopic probe was developed for monitoring esophageal and lung tissues and tested in patients in a pilot clinical study.","PeriodicalId":60385,"journal":{"name":"中国地球物理学会年刊","volume":"3 1","pages":"2283-2284 vol.3"},"PeriodicalIF":0.0000,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国地球物理学会年刊","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.1109/IEMBS.2002.1053283","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Photodynamic Therapy (PDT) uses light to activate photosensitive drug to yield oxidative injury to targeted tissues such as cancer. The ability of treatment light to penetrate a tissue and activate the drug that has accumulated in a target tissue depends on the tissue optical properties, especially the blood perfusion. An endoscopic spectroscopic probe was developed for monitoring esophageal and lung tissues and tested in patients in a pilot clinical study.
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