Clinical Characteristics of Egyptian Patients with Inflammatory Bowel Diseases Infected with COVID 19: Tertiary Center Experience from Egypt

A. Sherief, M. Shamkh, M. Sakr, W. H. A. Alaty, A. Bassuny, Ibrahim Abdelhakim Ibrahim, Safaa R Askar, Shimaa Y. Kamel, H. Rashad, M. Eltabbakh
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Abstract

During COVID 19 pandemic, inflammatory bowel disease patients were significantly worried about being at a higher risk of getting COVID 19 infection, the effect of their medications on the course of infection and the expected prognosis. This is a retrospective cohort study done in Our Inflammatory bowel disease unit, Tropical Medicine Department, Ain Shams University Hospitals, Cairo, Egypt. We retrospectively reviewed all our patients infected with COVID 19 (13 patients) during the period from March 2020 till mid-September 2020. Thirteen patients in our unit were infected with COVID 19. The mean age of infected patients was 39.92 ± 11.16 years. Most of them were females 11 (84.6%). Most of them had ulcerative colitis (61.5%) and only 38.5% had crohn's disease. Only six patients were admitted to isolation hospital, all of them were ulcerative colitis. The most common presenting symptoms were fever (84.6%), cough (76.9%) and diarrhea (61.5%). Three of ulcerative colitis patients encountered disease exacerbation. All our infected patients had a good prognosis regarding their inflammatory bowel disease and COVID 19 course. COVID-19 infection in inflammatory bowel disease patients may carry a favorable outcome despite the vulnerability of those patients.
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埃及感染新冠肺炎的炎症性肠病患者的临床特征:来自埃及三级中心的经验
在2019冠状病毒病大流行期间,炎症性肠病患者对感染风险较高、药物对感染过程的影响以及预期预后的担忧显著。这是一项在埃及开罗艾因沙姆斯大学医院热带医学科炎症性肠病科进行的回顾性队列研究。我们回顾性分析了2020年3月至2020年9月中旬期间所有感染COVID - 19的患者(13例)。我们单位有13例患者感染了COVID - 19。感染患者平均年龄为39.92±11.16岁。以女性11例(84.6%)居多。溃疡性结肠炎占61.5%,克罗恩病占38.5%。仅有6例患者入院隔离,均为溃疡性结肠炎。最常见的临床表现为发热(84.6%)、咳嗽(76.9%)和腹泻(61.5%)。3例溃疡性结肠炎患者出现疾病加重。所有感染患者的炎症性肠病和COVID - 19病程预后良好。炎症性肠病患者的COVID-19感染可能会带来有利的结果,尽管这些患者很脆弱。
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