Hong Li, G. Lv, J. Nan, Yonglei Liu, Xiaoman Luo, Yonggang Yan
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引用次数: 0
Abstract
A novel nano-hydroxyapatite/multi-(amino acid) copolymer (n-HA/MACP) composite was prepared by in situ polymerization and characterized by FT-IR XRD, mechanical measurement, in vitro degradation experiments and cell growth behavior. FT-IR and XRD results showed that the composite was composed of n-HA and an amide linkage structure and hydrogen bond was formed between n-HA and the copolymer. The composite showed different compressive strength of 176–263MPa, varying with the n-HA content in it. A 24-week incubation in phosphate buffered saline exhibited that the composite was degradable with the weight loss of 20.7wt% and the degradation showed no significant effects on the pH of the soaking medium.
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