Detection and epidemiological analysis of human papillomavirus infection subtypes in males in Dongyang, Zhejiang Province

Abstract

Objective To investigate the prevalence and epidemiologic distribution of human papillomavirus (HPV) infection in males in Dongyang area, and to provide scientific basis for the prevention and treatment of related diseases. Methods A retrospective analysis was made on the results of HPV 21 typing test in 712 male patients who were treated in Department of Andriatrics in Dongyang People’s Hospital from January 2018 to December 2018. Data differences were analyzed by SPSS 19.0 software. Results A total of 712 male samples were detected, of which 210 males were HPV positive, with the positive rate of 29.54%. Among the 210 positive samples, there were 141 cases of single infection, accounting for 67.14%, and 69 cases of multiple infection, accounting for 32.86%. After patients were grouped by ages, the highest positive ratio was 6/11 in the > 60 years old group, followed by the <20 years old group (37.50%, 15/40), 21-40 years old group (29.56%, 149/504) and 41-60 years old group (25.48%, 40/157) sequentially. And there were statistical differences among these groups in HIV positive rate (P<0.05). The positive rates in the third quarter and the fourth quarter were 35.20% (63/179) and 32.04% (58/181) respectively, which were significantly higher than the first quarter and the second quarter, of which the positive rates were 28.90% (50/173) and 21.79% (39/179) respectively (P<0.05). Among the 210 HIV patients, the most common symptoms were warts (26.67%, 56/210), followed by penile vegetation (18.10%, 38/210) and urinary tract infection (14.76%, 31/210). Conclusions The HPV infection rate of male in Dongyang area is high, with HPV6, HPV11 and HPV16 as the main types, and most of patients have single type infection. The positive rate of HIV was higher in patients younger than 20 years and patients older than 60 years. The positive detection rates in the third quarter and the fourth quarter are high, and the distribution shows a certain seasonal correlation. Most of HPV patients are diagnosed with warts in clinical. Key words: Human papilloma virus; Low-risk; High-risk; Infection