Adherence to Methadone Maintenance Treatment and its Predictors in Southeast of Iran

H. Ahmadipour
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Abstract

Background & Objectives: Adherence to Methadone Maintenance Treatment (MMT) is one of the most important challenges during treatment process. The positive effects of MMT will be established in case of appropriate adherence. Present study aimed to investigate MMT adherence and its predictors among addicts referred to rehab centers in Kerman province, south east of Iran. Methods: This research was carried out on 334 patients referred to rehab centers in Kerman province during 2017. Participants were selected through multistage random sampling method. Data collected using a questionnaire contained demographic data, addiction- related data and Persian version of MMT adherence questionnaire which assessed the adherence during the previous 3 and 30 days. Data analyzed by SPSS 19. Results: The mean age of the participants was 39.14 ± 10.93 years and most of them were male (85%). Seventy-three (21.8%) adhered to their treatment, 239 (71.6%) were nonadherent, and 22 (6.6%) highly nonadherent. Older age at the onset of addiction, longer duration of substance abuse, and no history of previous MMT were significant predictor for higher adherence. Interpretation & Conclusion: our study revealed about on fifth of addicts referred to rehab centers had good adherence to MMT. It is recommended the rehab centers to determine the factors associated with low adherence and use effective interventions to reduce them.
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伊朗东南部美沙酮维持治疗依从性及其预测因素
背景与目的:坚持美沙酮维持治疗(MMT)是治疗过程中最重要的挑战之一。在适当坚持的情况下,MMT的积极作用将得到确立。本研究旨在调查伊朗东南部克尔曼省康复中心成瘾者的MMT依从性及其预测因素。方法:对2017年在克尔曼省康复中心转诊的334例患者进行研究。研究对象采用多阶段随机抽样法进行选择。使用问卷收集的数据包括人口统计数据、成瘾相关数据和波斯语版MMT依从性问卷,该问卷评估了前3天和30天的依从性。数据分析采用SPSS 19。结果:参与者平均年龄为39.14±10.93岁,男性居多(85%)。73例(21.8%)坚持治疗,239例(71.6%)不坚持治疗,22例(6.6%)高度不坚持治疗。开始成瘾的年龄较大,药物滥用持续时间较长,以前没有MMT史是高依从性的显著预测因子。解释与结论:我们的研究显示,大约五分之一的成瘾者被转到康复中心,他们对MMT的依从性很好。建议康复中心确定与低依从性相关的因素,并使用有效的干预措施来减少它们。
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