Balloon Dilatation of the Pylorus After Gastric Pull-up in a Single Centre

Alexander Bech Rasmussen, B. N. Jepsen, F. hvid-Jensen, N. Katballe, D. Kjaer
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Abstract

Background: The mainstay of intended curative treatment for esophagus cancer is surgery. Symptoms of gastric outlet obstruction can occur in some patients postoperatively. Some of these patients require alleviating treatment which may include balloon dilatation of the pylorus. The aim of this study was to investigate the use for balloon dilatation of the pylorus following esophagectomy in patients treated for carcinoma of the esophagus with intent to cure. Methods: A retrospective study of 120 patients who underwent esophagectomy with gastric pull-up at Aarhus University Hospital, Denmark, between January 2017 and December 2018 and were followed until December 2020. Primary outcome was number of postoperative balloon dilatations of the pylorus. Results: A total of 63 patients (53%) went through at least 1 balloon dilatation of the pylorus, 40 (63%) needed more than 1 dilatation. The median time between esophagectomy and first dilatation was two months. There was a strong association between squamous cell carcinoma and postoperative dilatation compared to adenocarcinoma (OR=4.13). An association was also seen between ex-smokers and postoperative dilatation compared to non-smokers (OR=3.95). Conclusions: More than fifty percent of the patients needed postoperative balloon dilatation. The need for dilatations was strongest between the second and the ninth postoperative month. A nationwide multicentre study of gastric pull-up patients is needed in the future to develop clinical tools to assess the need for pyloric dilatation.
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单中心胃上拉后幽门球囊扩张
背景:食管癌的主要治疗方法是手术。部分患者术后可出现胃出口梗阻症状。其中一些患者需要减轻治疗,其中可能包括幽门球囊扩张。本研究的目的是探讨食管癌术后幽门球囊扩张术在治疗目的为治愈食管癌患者中的应用。方法:对2017年1月至2018年12月在丹麦奥胡斯大学医院接受食管切除术合并胃上拉治疗的120例患者进行回顾性研究,随访至2020年12月。主要观察指标为术后幽门球囊扩张次数。结果:63例(53%)患者行幽门球囊扩张1次以上,40例(63%)患者行幽门球囊扩张1次以上。从食管切除术到第一次扩张的中位时间为2个月。与腺癌相比,鳞状细胞癌与术后扩张有很强的相关性(OR=4.13)。与非吸烟者相比,戒烟者与术后扩张之间也存在关联(OR=3.95)。结论:超过50%的患者术后需要球囊扩张。术后第2个月至第9个月对扩张的需求最强。未来需要对胃引体抬高患者进行全国性的多中心研究,以开发临床工具来评估幽门扩张的必要性。
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