{"title":"Integrated treatment regime for duchenne muscular dystrophy","authors":"Sanjana Kareti, A. Kapadia, S. Dravida","doi":"10.15406/jsrt.2016.01.00030","DOIUrl":null,"url":null,"abstract":"Duchenne muscular dystrophy (DMD), a genetic neuromuscular disorder, has a pernicious influence on skeletal and cardiac muscle tissue and results in a significant decline in the life span of those affected. The destruction is mainly attributed to perpetuating inflammation and fibrosis. This review explores the potential of a comprehensive therapeutic approach with an objective to minimize ongoing damage and reconstitute normal tissue.","PeriodicalId":91560,"journal":{"name":"Journal of stem cell research & therapeutics","volume":"45 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of stem cell research & therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/jsrt.2016.01.00030","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Duchenne muscular dystrophy (DMD), a genetic neuromuscular disorder, has a pernicious influence on skeletal and cardiac muscle tissue and results in a significant decline in the life span of those affected. The destruction is mainly attributed to perpetuating inflammation and fibrosis. This review explores the potential of a comprehensive therapeutic approach with an objective to minimize ongoing damage and reconstitute normal tissue.