{"title":"Effect of Costus igneus Leaf Juice on Antidiabetic Activity of Glimepiride in Rats – A Suggestive Study","authors":"K. Akhil, B. .","doi":"10.30799/JNPR.075.19050103","DOIUrl":null,"url":null,"abstract":"Article history: Received 30 March 2019 Accepted 20 April 2019 Available online 06 May 2019 Due to therapeutic efficacy, Costus igneus Nak. (CI), (popularly known as insulin plant) is one medicinal plant in the limelight of having cure for diabetes. An oral diabetic agent Glimepiride was selected to evaluate the activity in per se and in combination with Costus igneus. The study drugs (glimepiride or Costus igneus leaf juice) were administered orally and blood glucose levels were determined using Glucometer at stipulated time intervals. It perhaps works in pathophysiologic/metabolic deranged conditions as observed by its per se effect in streptozotocin-induced diabetic rats’ contrast to its effect in normal rats. The results of our study confirm that, the combined action of glimepiride and Costus igneus leaf juice has greater antidiabetic effects than their individual effects (per se).","PeriodicalId":23586,"journal":{"name":"Volume 5,Issue 1,2019","volume":"4 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Volume 5,Issue 1,2019","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30799/JNPR.075.19050103","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Article history: Received 30 March 2019 Accepted 20 April 2019 Available online 06 May 2019 Due to therapeutic efficacy, Costus igneus Nak. (CI), (popularly known as insulin plant) is one medicinal plant in the limelight of having cure for diabetes. An oral diabetic agent Glimepiride was selected to evaluate the activity in per se and in combination with Costus igneus. The study drugs (glimepiride or Costus igneus leaf juice) were administered orally and blood glucose levels were determined using Glucometer at stipulated time intervals. It perhaps works in pathophysiologic/metabolic deranged conditions as observed by its per se effect in streptozotocin-induced diabetic rats’ contrast to its effect in normal rats. The results of our study confirm that, the combined action of glimepiride and Costus igneus leaf juice has greater antidiabetic effects than their individual effects (per se).
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
