Md. Saifuzzaman , Md. Sarowar Jahan Shamim , Kamanashis Mahaldar , Eunus Sheemul Ali , Md. Amirul Islam
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引用次数: 2
Abstract
Background
Persicaria acuminata Sach. (Family – Polygonaceae) commonly known as Bishkathali is a Bangladeshi native plant which is traditionally used in painful conditions.
Objective
The aim of the present study was to evaluate antinociceptive effect of the plant and to prove the scientific basis of traditional use.
Methods
The ethanolic extracts of leaf and stem of the plant were investigated using acetic acid induced writhing method on animal model.
Results
Oral administration of both leaf and stem extracts at the doses of 250 and 500 mg/kg body weight showed significant and dose-dependent inhibition of writhing response.
Conclusion
The study signifies the antinociceptive activity of the plant and supports its popular folkloric use in the management of pain.
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