Comparison of nicotine contents in local and imported cigarettes sold in Abidjan markets in Cte dIvoire: Lessons for regulation

Fandio Nanfa Veda, Diakité Aïssata
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Abstract

Tobacco use is one of the main leading causes of disease and death worldwide and according to the World Health Organization (WHO), constitutes a major issue to public health. Given the importance of nicotine as the major constituent of tobacco and its addictive potency on consumers, determining its content in cigarettes sold on Ivorian markets shows to be important. The aim of this study was to determine and compare nicotine content in imported and local brands of cigarettes marketed in the district of Abidjan. Nicotine was extracted from twenty-one brands of cigarettes with six being local and fifteen imported. Nicotine contents were measure by UV-Vis spectrophotometry at a wavelength of 508 nm. The assay method was linear on a concentration range of 0.2 to 1 mg/ml with a coefficient of determination of 0.9963 and a detection limit of 0.15 mg/ml. The average nicotine content in cigarettes of Ivory Coast brands was 1.73 ± 0.19 mg of nicotine/cigarette while that in imported brands was 2.25 ± 0.74 mg of nicotine/cigarette (p < 0.05). The lowest nicotine content was found in the local brand cigarette "Ex001", whereas the highest content was found in an imported brand cigarette "OR001 Pulse Bleu". The nicotine content of all tested cigarettes was higher than the European standard and a significative difference was found between the determined amounts of nicotine content in the cigarettes brands and the amounts displayed by the manufacturer on the cigarettes’ packs. Monitoring of nicotine content in cigarettes sold on the Ivorian market should be considered in prevention strategies against smoking addiction and tobacco-related diseases.
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科特迪瓦阿比让市场上销售的本地香烟和进口香烟尼古丁含量的比较:监管的经验教训
烟草使用是世界范围内导致疾病和死亡的主要原因之一,并且根据世界卫生组织(卫生组织)的说法,构成了公共卫生的一个重大问题。鉴于尼古丁作为烟草主要成分的重要性及其对消费者的成瘾性,确定科特迪瓦市场上销售的香烟中的尼古丁含量显得十分重要。本研究的目的是确定和比较在阿比让地区销售的进口和本地品牌香烟中的尼古丁含量。尼古丁是从21种香烟中提取的,其中6种是本地香烟,15种是进口香烟。采用紫外-可见分光光度法测定烟碱含量,波长508 nm。该方法在0.2 ~ 1 mg/ml浓度范围内呈线性,测定系数为0.9963,检出限为0.15 mg/ml。象牙海岸品牌香烟平均尼古丁含量为1.73±0.19 mg /支,进口品牌香烟平均尼古丁含量为2.25±0.74 mg /支(p < 0.05)。本地品牌香烟“Ex001”的尼古丁含量最低,而进口品牌香烟“OR001 Pulse Bleu”的尼古丁含量最高。所有受测香烟的尼古丁含量均高于欧洲标准,而香烟品牌上的尼古丁含量测定值与制造商在香烟包装上显示的含量有显著差异。在预防吸烟成瘾和烟草相关疾病的战略中,应考虑监测科特迪瓦市场上销售的香烟中的尼古丁含量。
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