Prevalence of intestinal metaplasia and its relation to Helicobacter pylori infection in Iraq

Refka M. Al-dahhan, Muhsin A. Sahib
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Abstract

Objectives: The aim of this study was to investigate the prevalence of intestinal metaplasia and its relation to H. Pylori infection, gastric atrophy, ulcer, age and gender in patients underwent esophagogastroduodenoscopy and gastric biopsy for upper gastrointestinal symptoms. Method: 200 gastric biopsy blocks examined for patients underwent esophagogastroduodenoscopy (EGD) and gastric biopsy, between January 2019 October 2020 at Gastroenterology and hepatology Hospital / Medical city / Baghdad / Iraq. Result: (67.5%) of patients examined in the study had H. pylori infection, while (20.5%) of the total number patients in the study had gastric intestinal metaplasia. There was significant association between Intestinal metaplasia with both active chronic inflammation and intestinal atrophy but there was no significant association between Intestinal metaplasia with both ulcer and H. pylori infection. Conclusion: gastric intestinal metaplasia encountered more in old age male patients with gastric atrophy and it is not solely related to h pylori, other risk factors could be responsible for it.
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伊拉克人肠化生的患病率及其与幽门螺杆菌感染的关系
目的:本研究旨在探讨食管胃十二指肠镜检查和上消化道活检患者肠化生的患病率及其与幽门螺杆菌感染、胃萎缩、溃疡、年龄和性别的关系。方法:于2019年1月/ 2020年10月/伊拉克巴格达消化肝病医院/医疗城对200例接受食管胃十二指肠镜检查(EGD)和胃活检的患者进行胃活检。结果:本研究检查的患者中有67.5%的患者存在幽门螺杆菌感染,而有20.5%的患者存在胃肠道化生。肠化生与活动性慢性炎症和肠萎缩均有显著相关性,但与溃疡和幽门螺杆菌感染无显著相关性。结论:老年男性胃萎缩患者肠上皮化生发生率较高,其发生并非单纯与幽门螺杆菌有关,可能与其他危险因素有关。
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审稿时长
12 weeks
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