Comparison Of P/F Ratio In Ventilated ARDS Patients Using Driving Pressure Strategy And Conventional Lung-Protective Strategy Method In ICU H. Adam Malik Hospital Medan

Abstract

Backgrounds: The progression of ARDS causes significant patient morbidity and mortality, with hypoxia being the basic mechanism of organ failure. Therefore, it is necessary to measure the P/F ratio to identify hypoxia as early as possible. Objectives: To compare the P/F ratio values in ventilated ARDS patients using driving pressure strategy method versus conventional lung-protective strategy in ICU of H. Adam Malik General Hospital Medan. Methods: This study was a randomized controlled trial conducted at ICUH. Haji Adam Malik General Hospital Medan of ventilated ARDS patients who were treated in ICU who met inclusion and exclusion criteria and were selected by consecutive sampling method. The value of the P/F ratio is determined by the driving pressure strategy method and the conventional lung protective strategy method. To analyze the difference in the P/F ratio between two intervention groups, the Mann-Whitney test was used. A confidence interval with an ap value of 0.05 is considered to be significantly significant. Results: The mean value of the P/F ratio in the lung protective group on the first day was 178.18 ± 46.5 and in the Driving pressure group was 164.81 ± 44.5 (p=0.608). On the second day, the mean P/F ratio in the lung protective group was 166.1 ± 30.8 and in the driving pressure group was 169.5 ± 12.8 (p=0.815). On the third day, the mean P/F ratio in the lung protective group was 177.2 ± 27.4 and in the driving pressure group was 175 ± 35 (p=0.726). Conclusion: There was no significant difference found in the P/F ratio value as measured by the lung protective strategy method and the driving pressure strategy method either from the first, second or third day.