Modern advancements, patents and applications of futuristic nanozymes: a comprehensive review

Abstract

In the last few years, nanozymes have emerged as an adequate substitute for natural enzymes. Recently, much attention has been paid to enzyme-mimic nanomaterials (nanozymes). Because of their distinct characteristics, they are a critical alternative to natural enzymes that can be produced at a subordinate cost and more efficiently. These nanomaterials have enzyme-like activity and have been cast off to detect and treat biomolecules such as DNA, proteins, cells, and tiny molecules such as glucose. Hence, the critical analysis of recent nanozyme is deemed essential for futuristic research, outcome-based results specified to current trends of analytical tools, and several disease monitoring for targeted oncology therapies like circulating tumor cells, MRI, PET, etc. In addition, the multivariate applications of nanozymes for biosensors, immunoassay formation, tumor cell detection with earlier remedies, and environmentally-sound engineering technologies are discussed to climax the modern advancements. The novelty and originality of this current review are to intensify the recent advancement, biomedical applications, types and mimicking activity, biomedical applications of nanozymes, implementation of the chemometric approach in nanozymes, and its futuristic approach. Finally, to promote the understanding of nanozymes and the development of novel and multifunctional nanozymes, we provide a comprehensive review of the nanozymes with their broadest applications and modern technologies involved in targeted drug discovery inventory with other diversified arenas and existing patents indicating future implications.