Pub Date : 2023-10-20DOI: 10.2174/0122106812255348231009101232
Nimasha Rathnasinghe, K.G. Kaushani, R.A. Jayasinghe, A.H.L.R. Nilmini, Nadeeka D. Tissera, Ruchira N. Wijesena, Gayan Priyadarshana
Abstract: Nanotechnology is a rapidly expanding field of study because of its numerous dermal applications and benefits in dermal care. It also represents progress in research and development by enhancing product efficacy through the adoption of novel technologies. Nanotechnology is increasingly being used in dermal applications to avoid some of the problems associated with traditional treatments. Dermal applications are the segment of the consumer products market that is expanding the fastest, and their popularity has exploded in recent years. In addition to wrinkles, hyperpigmentation, photoaging, hair damage, and dandruff, nanofibers are now frequently used in dermal treatments for skincare, hair, lips, and nails. These innovative dermal applications using nanofibers provide improved skin penetration, higher stability, site-specific targeting, controlled and prolonged drug release, and high entrapment effectiveness. The outcome of dermal applications can be improved with nanofibers by modifying their structure, functionality, chemical and mechanical resistance, and additional attributes. The importance of biopolymers in processing nanofibers, nanofiber processing methods, an overview of dermal applications' significance, and dermal applications based on nanofibers will all be discussed in this review.
{"title":"A Review on Novel Nanofiber-based Dermal Applications: Utilization of Polysaccharides","authors":"Nimasha Rathnasinghe, K.G. Kaushani, R.A. Jayasinghe, A.H.L.R. Nilmini, Nadeeka D. Tissera, Ruchira N. Wijesena, Gayan Priyadarshana","doi":"10.2174/0122106812255348231009101232","DOIUrl":"https://doi.org/10.2174/0122106812255348231009101232","url":null,"abstract":"Abstract: Nanotechnology is a rapidly expanding field of study because of its numerous dermal applications and benefits in dermal care. It also represents progress in research and development by enhancing product efficacy through the adoption of novel technologies. Nanotechnology is increasingly being used in dermal applications to avoid some of the problems associated with traditional treatments. Dermal applications are the segment of the consumer products market that is expanding the fastest, and their popularity has exploded in recent years. In addition to wrinkles, hyperpigmentation, photoaging, hair damage, and dandruff, nanofibers are now frequently used in dermal treatments for skincare, hair, lips, and nails. These innovative dermal applications using nanofibers provide improved skin penetration, higher stability, site-specific targeting, controlled and prolonged drug release, and high entrapment effectiveness. The outcome of dermal applications can be improved with nanofibers by modifying their structure, functionality, chemical and mechanical resistance, and additional attributes. The importance of biopolymers in processing nanofibers, nanofiber processing methods, an overview of dermal applications' significance, and dermal applications based on nanofibers will all be discussed in this review.","PeriodicalId":38913,"journal":{"name":"Nanoscience and Nanotechnology - Asia","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135618275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-20DOI: 10.2174/0122106812256179231011062129
Prajwal S. Pagare, Gitesh G. Patil, Riddhi S. Soni, Sushal D. Pingale, Rakesh D. Amrutkar, Vaibhav Bhamare
Abstract: Nanotechnology has emerged as one of the key scientific initiatives of the early 21st century. Scientists take advantage of the distinctive features of atomic and molecular assemblages constructed at the nanometer scale. In order to gather the necessary collective expertise needed to develop these revolutionary technologies, classical sciences such as chemistry, physics, materials science, biology including genomics are brought together in the field of nanotechnology. Systems and materials related to nanotechnology have parts and structures which are due to their nanoscale size, exhibit innovative, greatly improved chemical, physical, and biological properties, processes and phenomena. In a variety of sectors, including tissue engineering, drug delivery systems and physiology, nanotechnology and nanoengineering have the potential to significantly enhance science and technology
{"title":"Nanotechnology: A Promising Area in Medical Science","authors":"Prajwal S. Pagare, Gitesh G. Patil, Riddhi S. Soni, Sushal D. Pingale, Rakesh D. Amrutkar, Vaibhav Bhamare","doi":"10.2174/0122106812256179231011062129","DOIUrl":"https://doi.org/10.2174/0122106812256179231011062129","url":null,"abstract":"Abstract: Nanotechnology has emerged as one of the key scientific initiatives of the early 21st century. Scientists take advantage of the distinctive features of atomic and molecular assemblages constructed at the nanometer scale. In order to gather the necessary collective expertise needed to develop these revolutionary technologies, classical sciences such as chemistry, physics, materials science, biology including genomics are brought together in the field of nanotechnology. Systems and materials related to nanotechnology have parts and structures which are due to their nanoscale size, exhibit innovative, greatly improved chemical, physical, and biological properties, processes and phenomena. In a variety of sectors, including tissue engineering, drug delivery systems and physiology, nanotechnology and nanoengineering have the potential to significantly enhance science and technology","PeriodicalId":38913,"journal":{"name":"Nanoscience and Nanotechnology - Asia","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135620001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-10DOI: 10.2174/0122106812264073230929170021
Shivani V. Kadam, Chandrakant S. Magdum, Sandeep R. Kane, Mangesh A. Bhutkar, Dheeraj S. Randive, Somnath D. Bhinge, Kailas D. Sonawane
Background:: In Indian traditional medicine, the seeds and bark of Wrightia tinctoria are utilized as remedies for antidiarrheal and antidysenteric purposes, as well as for other medicinal uses. Aim:: The primary aim of the study was to explore the green synthesis of silver and gold nanoparticles by employing an extract obtained from the Wrightia tinctoria plant and to explore their potential medicinal properties. Objective:: This study involved the characterization of the nanoparticles in terms of their properties and quality, as well as an investigation of their potential anti-bacterial, anticancer, and antiinflammatory properties. Method:: Various characterization techniques, including UV spectroscopy, XRD spectra, FTIR, SEM, particle size and zeta potential analysis, were used in this study for the synthesized nanoparticles. Our study investigated the impact of concentration, pH, and incubation time on nanoparticle synthesis, providing a comprehensive description of the synthesis procedure for both silver and gold nanoparticles. Result:: Experimental findings confirmed that silver and gold nanoparticles derived from Wrightia tinctoria exhibited irregular shape, with an average diameter ranging from approximately 0.08 to 0.34 μm and 0.09 to 0.30 μm, respectively. Appreciably, the biologically synthesized WTAgNPs and WTAuNPs demonstrated promising antibacterial, anticancer, and anti-inflammatory properties without any signs of toxicity. The enhanced biological activity of WTAgNPs and WTAuNPs can be attributed to their distinctive properties at the nanoscale, as both exhibit lower polydispersity and average particle size, contributing to increased reactivity and interactions with biological systems. conclusion: As a result, these nanoparticles, synthesized through the biogenic approach using Wrightia tinctoria extract, have immense potential for a wide range of pharmaceutical applications. Conclusion:: The nanoparticles synthesized through the biogenic approach using Wrightia tinctoria extract have immense potential for a wide range of pharmaceutical applications. other: None
{"title":"Investigation of Therapeutic Potential of Biosynthesized Silver and Gold Nanoparticles Using Extract of Wrightia tinctoria","authors":"Shivani V. Kadam, Chandrakant S. Magdum, Sandeep R. Kane, Mangesh A. Bhutkar, Dheeraj S. Randive, Somnath D. Bhinge, Kailas D. Sonawane","doi":"10.2174/0122106812264073230929170021","DOIUrl":"https://doi.org/10.2174/0122106812264073230929170021","url":null,"abstract":"Background:: In Indian traditional medicine, the seeds and bark of Wrightia tinctoria are utilized as remedies for antidiarrheal and antidysenteric purposes, as well as for other medicinal uses. Aim:: The primary aim of the study was to explore the green synthesis of silver and gold nanoparticles by employing an extract obtained from the Wrightia tinctoria plant and to explore their potential medicinal properties. Objective:: This study involved the characterization of the nanoparticles in terms of their properties and quality, as well as an investigation of their potential anti-bacterial, anticancer, and antiinflammatory properties. Method:: Various characterization techniques, including UV spectroscopy, XRD spectra, FTIR, SEM, particle size and zeta potential analysis, were used in this study for the synthesized nanoparticles. Our study investigated the impact of concentration, pH, and incubation time on nanoparticle synthesis, providing a comprehensive description of the synthesis procedure for both silver and gold nanoparticles. Result:: Experimental findings confirmed that silver and gold nanoparticles derived from Wrightia tinctoria exhibited irregular shape, with an average diameter ranging from approximately 0.08 to 0.34 μm and 0.09 to 0.30 μm, respectively. Appreciably, the biologically synthesized WTAgNPs and WTAuNPs demonstrated promising antibacterial, anticancer, and anti-inflammatory properties without any signs of toxicity. The enhanced biological activity of WTAgNPs and WTAuNPs can be attributed to their distinctive properties at the nanoscale, as both exhibit lower polydispersity and average particle size, contributing to increased reactivity and interactions with biological systems. conclusion: As a result, these nanoparticles, synthesized through the biogenic approach using Wrightia tinctoria extract, have immense potential for a wide range of pharmaceutical applications. Conclusion:: The nanoparticles synthesized through the biogenic approach using Wrightia tinctoria extract have immense potential for a wide range of pharmaceutical applications. other: None","PeriodicalId":38913,"journal":{"name":"Nanoscience and Nanotechnology - Asia","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136358253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-05DOI: 10.2174/0122106812246316230920095319
CHIME AMARACHI SALOME, Anthony Attama
Abstract: Lipid based nanoparticle (LNP) structures commonly used for drug delivery already in clinical use are generally classified into three viz vesicular systems, emulsion based systems and lipid nanoparticles. The details of the types, basic structural characteristics in drug delivery, clinical trials, and patents have been discussed in this work. Moreover, despite the therapeutic efficacies of LNPs, there are some toxicity challenges associated with their use. These toxicities may be cytotoxicity or genotoxicity; to overcome some of these challenges, some measures could be taken during preformulation stages in order to circumvent it. These measures have been extensively discussed in this work. LNPs are used in the targeting of immune cells, which are direct participants in a variety of diseases, hence, are attractive targets for therapy. Cell specific targeting of therapeutic agent(s) helps to concentrate and localize the therapeutic effect and, hence, lowers the systemic side effects, while simultaneously increasing the management outcome. Nanotechnology and particle engineering helps distinguish each immune cell from the other to deliver therapeutic agents and ensure in vivo stability as well as sustained drug release. Surface modification of LNP is an important characteristic utilized in targeting therapeutic agents and allows the utilization of various specific properties expressed in each immune cell. These targeting strategies have been explored in this work exhaustively, and some of the companies and academic labs that develop LNP have been discussed. Also, new ways of developing novel patentable LNP have been discussed.
{"title":"Lipid-based Nanoparticles (LNP) Structures used for Drug Delivery and Targeting: Clinical Trials and Patents","authors":"CHIME AMARACHI SALOME, Anthony Attama","doi":"10.2174/0122106812246316230920095319","DOIUrl":"https://doi.org/10.2174/0122106812246316230920095319","url":null,"abstract":"Abstract: Lipid based nanoparticle (LNP) structures commonly used for drug delivery already in clinical use are generally classified into three viz vesicular systems, emulsion based systems and lipid nanoparticles. The details of the types, basic structural characteristics in drug delivery, clinical trials, and patents have been discussed in this work. Moreover, despite the therapeutic efficacies of LNPs, there are some toxicity challenges associated with their use. These toxicities may be cytotoxicity or genotoxicity; to overcome some of these challenges, some measures could be taken during preformulation stages in order to circumvent it. These measures have been extensively discussed in this work. LNPs are used in the targeting of immune cells, which are direct participants in a variety of diseases, hence, are attractive targets for therapy. Cell specific targeting of therapeutic agent(s) helps to concentrate and localize the therapeutic effect and, hence, lowers the systemic side effects, while simultaneously increasing the management outcome. Nanotechnology and particle engineering helps distinguish each immune cell from the other to deliver therapeutic agents and ensure in vivo stability as well as sustained drug release. Surface modification of LNP is an important characteristic utilized in targeting therapeutic agents and allows the utilization of various specific properties expressed in each immune cell. These targeting strategies have been explored in this work exhaustively, and some of the companies and academic labs that develop LNP have been discussed. Also, new ways of developing novel patentable LNP have been discussed.","PeriodicalId":38913,"journal":{"name":"Nanoscience and Nanotechnology - Asia","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-12DOI: 10.2174/2210681213666230912144049
Popat Kumbhar, Onkar Patil, Preeti Karade, Rajdeep Bhokare, Gaurav Gupta, Sachin Kumar Singh, Kamal Dua, John Disouza, Vandana Patravale
Abstract: Infectious diseases caused by different pathogens are responsible for high mortality across the globe. Multi-drug resistance (MDR) of microorganisms towards different antibiotics has posed a great challenge in treating infectious diseases efficiently. The metal-based nanoparticles (MNPs) have demonstrated great promise in treating infectious diseases because of their inherent antimicrobial potential. Besides, these NPs show site-specific delivery of antibiotic therapeutics, thereby minimizing dose, dose frequency, and side effects. Further, the synergistic effect of MNPs with an antibiotic can reduce the MDR. However, the fabrication of MNPs using an apt fabrication technique with proper control of charge, size, and morphology is highly required to achieve better therapeutic performance. This review focuses on MNPs as a potential avenue to treat infectious diseases. The role of MNPs in combating MDR, different sorts of MNPs, and their fabrication techniques are discussed. Furthermore, assorted types of MNPs employed in antibiotic delivery to treat infectious diseases are discussed with manifold case studies. In short, MNPs alone or as a carrier of antibiotics seems to be an effective strategy in wiping out infectious diseases.
{"title":"Metal-based nanoparticles in the treatment of infectious diseases","authors":"Popat Kumbhar, Onkar Patil, Preeti Karade, Rajdeep Bhokare, Gaurav Gupta, Sachin Kumar Singh, Kamal Dua, John Disouza, Vandana Patravale","doi":"10.2174/2210681213666230912144049","DOIUrl":"https://doi.org/10.2174/2210681213666230912144049","url":null,"abstract":"Abstract: Infectious diseases caused by different pathogens are responsible for high mortality across the globe. Multi-drug resistance (MDR) of microorganisms towards different antibiotics has posed a great challenge in treating infectious diseases efficiently. The metal-based nanoparticles (MNPs) have demonstrated great promise in treating infectious diseases because of their inherent antimicrobial potential. Besides, these NPs show site-specific delivery of antibiotic therapeutics, thereby minimizing dose, dose frequency, and side effects. Further, the synergistic effect of MNPs with an antibiotic can reduce the MDR. However, the fabrication of MNPs using an apt fabrication technique with proper control of charge, size, and morphology is highly required to achieve better therapeutic performance. This review focuses on MNPs as a potential avenue to treat infectious diseases. The role of MNPs in combating MDR, different sorts of MNPs, and their fabrication techniques are discussed. Furthermore, assorted types of MNPs employed in antibiotic delivery to treat infectious diseases are discussed with manifold case studies. In short, MNPs alone or as a carrier of antibiotics seems to be an effective strategy in wiping out infectious diseases.","PeriodicalId":38913,"journal":{"name":"Nanoscience and Nanotechnology - Asia","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135885456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-11DOI: 10.2174/2210681213666230911161526
Tika Ram Bhandari, Yub Narayan Thapa, Chiranjibi Dhakal, Rameshwar Adhikari
Abstract: MXene-based multicomponent materials are 2D substances derived from transition metal (M) with carbide/nitride combinations having several propitious uses, including application in energy storage devices for high-performance electrodes for Lithium-ion batteries (LIBs) fabrication. The suitability of these new classes of materials for LIB electrodes can be attributed to their high conductivity combined with their excellent surface properties desirable for electrode applications, such as fast charge-discharge capability, high storage capacity and high rate capacity. However, there are several challenges possessed by MXene-based nanomaterials in the application of their electrodes in future flexible and wearable devices, demanding more research work and development strategies. After a brief overview of MXenes used in batteries, this paper deals with the synthesis, morphology-properties correlations, and their performance. Finally, this paper headlines the advantages, limitations, and challenges of MXene-based electrodes for LIBs, ending with concluding remarks.
{"title":"MXenes-based Multifunctional Nanomaterials for Lithium-Ion Batteries: Opportunities and Challenges","authors":"Tika Ram Bhandari, Yub Narayan Thapa, Chiranjibi Dhakal, Rameshwar Adhikari","doi":"10.2174/2210681213666230911161526","DOIUrl":"https://doi.org/10.2174/2210681213666230911161526","url":null,"abstract":"Abstract: MXene-based multicomponent materials are 2D substances derived from transition metal (M) with carbide/nitride combinations having several propitious uses, including application in energy storage devices for high-performance electrodes for Lithium-ion batteries (LIBs) fabrication. The suitability of these new classes of materials for LIB electrodes can be attributed to their high conductivity combined with their excellent surface properties desirable for electrode applications, such as fast charge-discharge capability, high storage capacity and high rate capacity. However, there are several challenges possessed by MXene-based nanomaterials in the application of their electrodes in future flexible and wearable devices, demanding more research work and development strategies. After a brief overview of MXenes used in batteries, this paper deals with the synthesis, morphology-properties correlations, and their performance. Finally, this paper headlines the advantages, limitations, and challenges of MXene-based electrodes for LIBs, ending with concluding remarks.","PeriodicalId":38913,"journal":{"name":"Nanoscience and Nanotechnology - Asia","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136023828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acne is one of the most prevalent skin conditions among adolescents, which can often continue to adulthood. It is characterized by the appearance of comedones along with blackheads, whiteheads, papules, pimples, and pinheads on the neck, face, and back. The most common cause of acne is the bacteria Propionibacterium acnes, but factors like hormonal imbalance, anxiety, and genetic makeup can often be responsible. Despite the availability of numerous anti-acne agents, their efficacy is often limited due to poor skin penetration and adverse effects. Nanocarriers have emerged as a promising approach for the targeted delivery of anti-acne agents to the skin. This review discusses the potential of nanocarriers, including vesicular systems, biphasic systems, polymeric systems, fullerenes, and carbon nanoparticles, for enhanced skin penetration and controlled release of anti-acne agents. Various studies have reported using nanocarriers to successfully deliver agents such as benzoyl peroxide, salicylic acid, and retinoids, resulting in improved efficacy and reduced side effects. Using nanocarriers has shown promise for developing combination therapies targeting multiple aspects of acne pathogenesis. However, further research is needed to optimize the formulation and assess the safety and efficacy of nanocarrier-based anti-acne therapies.
{"title":"Exploring the potential of nanocarriers for targeted delivery of anti-acne agents: A review","authors":"Prabhat Dhingra, Unnati Garg, Neha Jain, Shreya Kaul, Upendra Nagaich","doi":"10.2174/2210681213666230830125348","DOIUrl":"https://doi.org/10.2174/2210681213666230830125348","url":null,"abstract":"\u0000\u0000Acne is one of the most prevalent skin conditions among adolescents, which can often continue\u0000to adulthood. It is characterized by the appearance of comedones along with blackheads, whiteheads,\u0000papules, pimples, and pinheads on the neck, face, and back. The most common cause of acne is the bacteria Propionibacterium acnes, but factors like hormonal imbalance, anxiety, and genetic makeup can often\u0000be responsible. Despite the availability of numerous anti-acne agents, their efficacy is often limited due to\u0000poor skin penetration and adverse effects. Nanocarriers have emerged as a promising approach for the\u0000targeted delivery of anti-acne agents to the skin. This review discusses the potential of nanocarriers, including vesicular systems, biphasic systems, polymeric systems, fullerenes, and carbon nanoparticles, for\u0000enhanced skin penetration and controlled release of anti-acne agents. Various studies have reported using\u0000nanocarriers to successfully deliver agents such as benzoyl peroxide, salicylic acid, and retinoids, resulting in improved efficacy and reduced side effects. Using nanocarriers has shown promise for developing\u0000combination therapies targeting multiple aspects of acne pathogenesis. However, further research is needed to optimize the formulation and assess the safety and efficacy of nanocarrier-based anti-acne therapies.\u0000","PeriodicalId":38913,"journal":{"name":"Nanoscience and Nanotechnology - Asia","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87569483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-25DOI: 10.2174/2210681213666230825112219
D. Dahanayake, Hansani Yashomala, C. Sandaruwan, Haneen Packeer Ally, S. Gunasekara, Veranja Karunarathne, G. Amaratunga
The present study examines the atomic-scale structures of Graphene Oxide (GO) and Reduced Graphene Oxide (RGO). Electron microscopic studies on Sri Lankan vein graphite are considerably less; hence, this study focuses on the atomic-scale study of Sri Lankan vein graphite, using advanced electron microscopic techniques. The purpose of this research is to utilize the data obtained to explore the multidisciplinary characteristics of graphene to the maximum prospectively. We report an atomic-scale study on Sri Lankan vein graphite (purest) derivatives using advanced electron microscopic techniques, including High-Resolution Transmission Electron Microscope (HRTEM), Scanning Transmission Electron Microscope (STEM), and Electron Energy Loss Spectroscopy (EELS). The present study examines the atomic-scale structures of Graphene Oxide (GO) and Reduced Graphene Oxide (RGO). The results obtained exhibited an inter-atomic layer distance of 3.54 Å for RGO. The EELS study performed with the electron dose optimization for GO and RGO distinguished the differences in the C K edge with the oxygen functionalities. The XPS study confirmed the changes in oxygen functionalities obtained with EELS. The advanced electron microscopic techniques and other molecular spectroscopic analysis techniques allowed us to obtain a comprehensive study on Sri Lankan vein graphene-based structural and chemical features on an atomic scale.
{"title":"Derivatives of Sri Lankan Vein Graphite: Atomic Scale Study of Graphene Oxide and Reduced Graphene Oxide","authors":"D. Dahanayake, Hansani Yashomala, C. Sandaruwan, Haneen Packeer Ally, S. Gunasekara, Veranja Karunarathne, G. Amaratunga","doi":"10.2174/2210681213666230825112219","DOIUrl":"https://doi.org/10.2174/2210681213666230825112219","url":null,"abstract":"\u0000\u0000The present study examines the atomic-scale structures of Graphene Oxide (GO) and Reduced Graphene Oxide (RGO).\u0000\u0000\u0000\u0000Electron microscopic studies on Sri Lankan vein graphite are considerably less; hence, this study focuses on the atomic-scale study of Sri Lankan vein graphite, using advanced electron microscopic techniques.\u0000\u0000\u0000\u0000The purpose of this research is to utilize the data obtained to explore the multidisciplinary characteristics of graphene to the maximum prospectively.\u0000\u0000\u0000\u0000We report an atomic-scale study on Sri Lankan vein graphite (purest) derivatives using advanced electron microscopic techniques, including High-Resolution Transmission Electron Microscope (HRTEM), Scanning Transmission Electron Microscope (STEM), and Electron Energy Loss Spectroscopy (EELS). The present study examines the atomic-scale structures of Graphene Oxide (GO) and Reduced Graphene Oxide (RGO).\u0000\u0000\u0000\u0000The results obtained exhibited an inter-atomic layer distance of 3.54 Å for RGO. The EELS study performed with the electron dose optimization for GO and RGO distinguished the differences in the C K edge with the oxygen functionalities. The XPS study confirmed the changes in oxygen functionalities obtained with EELS.\u0000\u0000\u0000\u0000The advanced electron microscopic techniques and other molecular spectroscopic analysis techniques allowed us to obtain a comprehensive study on Sri Lankan vein graphene-based structural and chemical features on an atomic scale.\u0000","PeriodicalId":38913,"journal":{"name":"Nanoscience and Nanotechnology - Asia","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86321541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-23DOI: 10.2174/2210681213666230823160616
Saloni Sharma, Gowthamarajan Kuppusamy, Parikshit Roy Chowdhury, Divya Pamu
Colorectal Cancer (CRC) is a highly prevalent and the most frequent reason for death. The choice of nanotheranostic technology for the management of colorectal cancer is one of the emerging strategies to overcome Colorectal Cancer (CRC). Magnetic nanoparticles are employed in this case because they have biomedical applications, such as diagnostic imaging, thermal treatment, and medication transport. There has been evidence of the usage of various chemicals on the surface of nano-particles, such as ligands, to highlight the contact with tumour cells at the target region in order to induce effective cytotoxic drug release. This review will highlight current breakthroughs in targeting magnetic nanoparticles against colorectal cancer, as well as the selection of ligands and their cellular targets with ionizing radiation employing in vitro and in vivo energies for Colorectal Cancer management.
{"title":"Nanotheranostic Approach for the management of colorectal cancer","authors":"Saloni Sharma, Gowthamarajan Kuppusamy, Parikshit Roy Chowdhury, Divya Pamu","doi":"10.2174/2210681213666230823160616","DOIUrl":"https://doi.org/10.2174/2210681213666230823160616","url":null,"abstract":"\u0000\u0000Colorectal Cancer (CRC) is a highly prevalent and the most frequent reason for death. The choice of nanotheranostic technology for the management of colorectal cancer is one of the emerging strategies to overcome Colorectal Cancer (CRC). Magnetic nanoparticles are employed in this case because they have biomedical applications, such as diagnostic imaging, thermal treatment, and medication transport. There has been evidence of the usage of various chemicals on the surface of nano-particles, such as ligands, to highlight the contact with tumour cells at the target region in order to induce effective cytotoxic drug release. This review will highlight current breakthroughs in targeting magnetic nanoparticles against colorectal cancer, as well as the selection of ligands and their cellular targets with ionizing radiation employing in vitro and in vivo energies for Colorectal Cancer management.\u0000","PeriodicalId":38913,"journal":{"name":"Nanoscience and Nanotechnology - Asia","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89514102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-13DOI: 10.2174/2210681213666230713112336
Sunita Mishra, Rajani Singh
Nanotechnology is a rising field in many research areas now a day. It brings up a vast scope in many areas like agriculture, food preservation, pharmaceuticals, etc. As the world population is increasing rapidly, there is an urgent need to cope with the rising demand for food. Nanotechnology is one of the most pioneering and promising technologies for the transformation of food and agro-industries. Nutrients get depleted yearly due to the continuous farming system in particular farms. Although chemical fertilizers added regularly may sustain the yield, the quality of the yield gets affected nutritionally, which may seriously affect human health. One of the most promising ways to address the drawbacks of conventional agricultural methods is nanotechnology. Nanotechnology is a sustainable way of farming that improves the quality, quantity, and security of foods. The importance of nanotechnological application in farming is to offer healthy and complete food from farm to fork, including functional and neutraceutical foods, and also to improve the efficacy, bioavailability, and nutritional status of food. Agro nanotechnology is proven to be an eco-friendly method of farming; this technology can decrease the toxicity of soil and increase its fertility. By incorporating innovative techniques to improve nutritional quality and food safety, the products obtained from the application of nanotechnology to agricultural and food systems might put farmers and manufacturers in a strong competitive position and benefit nearly everyone. Therefore, the use of nanoparticles as fertilizer enhances the growth, nutritional quality, affordability, and sustainability of the crop.
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