IN ROAD TRAFFIC ACCIDENTS, ARE THE PATTERN, SEVERITY, AND OUTCOME OF DRIVERS’ INJURIES AFFECTED BY MARIJUANA ABUSE?

Amira A. Wahdan, A. Hafez
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Abstract

Introduction: Road traffic accidents (RTAs) represent a leading contributor to the global disease burden. Drivers involved in some RTAs were found to be under the influence of different drugs. Marijuana effects on driving risks are not thoroughly understood. The study aimed to compare the pattern, severity, and clinical outcome of injuries between marijuana-smoking drivers and non-drugged drivers in RTAs. Patients and Methods: This prospective, comparative study was carried out on 78 drivers admitted to the emergency department, Tanta University Emergency Hospital during the period from the start of January to the end of December 2018. All drivers were subjected to history taking, clinical examination, assessment of injury severity score (ISS) and revised trauma score (RTS), and detection of tetrahydrocannabinol (THC) in urine. Results: Thirty-six drivers tested positive for THC with a median level of 314.6 ng/ml. There was a lack of significant association between marijuana smoking and the site of injuries. The marijuana-positive group had a significantly higher frequency of skull fractures, ruptured spleen, intraperitoneal hemorrhage, and abrasions on the body surface when compared to the marijuana-negative group. The median ISS was non-significantly higher, and the mortality was significantly higher in the marijuana-positive group. The THC level correlated significantly and strongly with both ISS and RTS. A significantly higher median THC level was detected in non-survivors compared to survivors. Conclusion: It could be concluded that Marijuana smoking is associated with an increased mortality rate in victims of RTAs. There are strong correlations between THC level and both ISS and RTS, suggesting a dose-dependent effect of marijuana smoking.
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在道路交通事故中,司机受伤的模式、严重程度和结果是否受到大麻滥用的影响?
导言:道路交通事故是造成全球疾病负担的一个主要因素。参与一些rta的司机被发现受到了不同药物的影响。大麻对驾驶风险的影响尚未完全了解。该研究旨在比较rta中吸食大麻的司机和未吸食毒品的司机之间的伤害模式、严重程度和临床结果。患者与方法:对2018年1月初至12月底在坦塔大学急救医院急诊科就诊的78名司机进行前瞻性比较研究。所有驾驶员均接受病史记录、临床检查、损伤严重程度评分(ISS)和修订创伤评分(RTS)评估以及尿液中四氢大麻酚(THC)的检测。结果:36名驾驶员THC检测呈阳性,中位水平为314.6 ng/ml。吸食大麻和受伤部位之间没有明显的联系。与大麻阴性组相比,大麻阳性组颅骨骨折、脾脏破裂、腹腔内出血和体表擦伤的频率显著高于大麻阴性组。大麻阳性组中位ISS无显著性增高,死亡率显著增高。THC水平与ISS和RTS均显著且强烈相关。与幸存者相比,非幸存者中THC水平明显更高。结论:可以得出结论,大麻吸烟与rta患者死亡率增加有关。四氢大麻酚水平与ISS和RTS之间存在很强的相关性,表明吸食大麻具有剂量依赖性。
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