{"title":"Biomimic Antibacterial Sensing Silk Bio-Patch","authors":"Zhiheng Gao, T. Tao, Keyin Liu","doi":"10.1109/Transducers50396.2021.9495518","DOIUrl":null,"url":null,"abstract":"We report a class of biomimic silk-based bio-patches with inherent bacterial inhibition and infection monitoring function. Mechanical properties of the silk bio-patch can be well-tuned to match the elastic modulus of human patches such as dura mater and hernia patch. The silk bio-patch can be functionalized by facilely adding bioactive drugs and bio-factors. Bacterial inhibition can be achieved by the micro-patterns of the optical diffraction element (DOE) on the silk bio-patch. Besides, the DOE in the silk bio-patch can be used to monitor tissue infection by detecting the change of the diffraction pattern. Our approach offers potential to developing multifunctional implantable devices in biomedical applications.","PeriodicalId":6814,"journal":{"name":"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)","volume":"42 1","pages":"1420-1423"},"PeriodicalIF":0.0000,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/Transducers50396.2021.9495518","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We report a class of biomimic silk-based bio-patches with inherent bacterial inhibition and infection monitoring function. Mechanical properties of the silk bio-patch can be well-tuned to match the elastic modulus of human patches such as dura mater and hernia patch. The silk bio-patch can be functionalized by facilely adding bioactive drugs and bio-factors. Bacterial inhibition can be achieved by the micro-patterns of the optical diffraction element (DOE) on the silk bio-patch. Besides, the DOE in the silk bio-patch can be used to monitor tissue infection by detecting the change of the diffraction pattern. Our approach offers potential to developing multifunctional implantable devices in biomedical applications.
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