Katelyn J Kotlarek, Sierra Levene, Annalisa V Piccorelli, Gregory C Allen, Krystle Barhaghi, Ilana Neuberger
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引用次数: 0
Abstract
Objective: To quantify differences in levator veli palatini (LVP) muscle dimensions based on age, sex, and race and determine the typical range of asymmetry between the left and right sides of the LVP under age 2.
Design: Retrospective cohort study.
Setting: Children's tertiary care hospital.
Participants: A retrospective chart review of non-cleft patients under 2 who received a volumetric FLAIR MRI sequence within the past 18 months identified 216 patient scans. Exclusion criteria left 200 scans for analysis. Measurements of the LVP were obtained consistent with previous literature.
Interventions: Corrected age, sex, and race.
Main outcome measure(s): LVP muscle dimensions.
Results: A significant (P < .0001) difference between corrected age groups based on the overall combination of LVP variables after controlling for sex and race. Significant age differences included average extravelar length (P < .0001), average intravelar length (P < .0001), midline thickness (P < .0001), and average (P < .0001) and difference (P = .0413) in insertion thickness. Significant sex differences included average intravelar length (P = .0412) and average insertion thickness (P = .0281). Significant race differences included average insertion thickness (P = .0334) and difference in intravelar length (P = .0473). Differences between left and right total length (P = .0491) and angle of origin (P < .0001) were significant.
Conclusions: Differences in LVP morphology were observed in individuals under 2 years or age related to age, sex, and race. While asymmetry was significant in some dimensions, it varied by age range.
期刊介绍：
The Cleft Palate-Craniofacial Journal (CPCJ) is the premiere peer-reviewed, interdisciplinary, international journal dedicated to current research on etiology, prevention, diagnosis, and treatment in all areas pertaining to craniofacial anomalies. CPCJ reports on basic science and clinical research aimed at better elucidating the pathogenesis, pathology, and optimal methods of treatment of cleft and craniofacial anomalies. The journal strives to foster communication and cooperation among professionals from all specialties.
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