Leveraging Deep Representations of Radiology Reports in Survival Analysis for Predicting Heart Failure Patient Mortality.

Q3 Business, Management and Accounting International Journal of Business Excellence Pub Date : 2021-06-01 DOI:10.18653/v1/2021.naacl-main.358
Hyun Gi Lee, Evan Sholle, Ashley Beecy, Subhi Al'Aref, Yifan Peng
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Abstract

Utilizing clinical texts in survival analysis is difficult because they are largely unstructured. Current automatic extraction models fail to capture textual information comprehensively since their labels are limited in scope. Furthermore, they typically require a large amount of data and high-quality expert annotations for training. In this work, we present a novel method of using BERT-based hidden layer representations of clinical texts as covariates for proportional hazards models to predict patient survival outcomes. We show that hidden layers yield notably more accurate predictions than predefined features, outperforming the previous baseline model by 5.7% on average across C-index and time-dependent AUC. We make our work publicly available at https://github.com/bionlplab/heart_failure_mortality.

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在生存分析中利用放射学报告的深度表征预测心衰患者的死亡率。
在生存分析中利用临床文本是很困难的,因为它们在很大程度上是非结构化的。目前的自动提取模型无法全面捕捉文本信息,因为它们的标签范围有限。此外,这些模型通常需要大量数据和高质量的专家注释来进行训练。在这项工作中,我们提出了一种新方法,即使用基于 BERT 的临床文本隐藏层表示作为比例危险模型的协变量来预测患者的生存结果。我们的研究表明,与预定义特征相比,隐藏层的预测结果明显更准确,在 C 指数和随时间变化的 AUC 方面平均比以前的基线模型高出 5.7%。我们在 https://github.com/bionlplab/heart_failure_mortality 上公开了我们的研究成果。
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来源期刊
International Journal of Business Excellence
International Journal of Business Excellence Business, Management and Accounting-Business and International Management
CiteScore
1.60
自引率
0.00%
发文量
80
期刊介绍: Business excellence relies heavily on the type of strategies, techniques and tools for measuring and benchmarking the business performance. Subsequently, identifying best practices and their implementation eventually decides excellence in business. Given the importance of business excellence, a journal devoted to performance evaluation and best practices, especially in order to be competitive in the global market, is essential. IJBEX addresses new developments in business excellence and best practices, and methodologies to determine these in both manufacturing and service organisations. Topics covered include: -Performance measures and metrics in business management- Methodologies and tools for performance measurement- Benchmarking business performance- Business excellence in various functional areas- Best practices in business management- World class business and operational strategies and techniques- Alignment between different levels of strategies- Understanding the customer requirements- Process design and management- Knowledge management for improved performance- Systems approach for determining the best practices- Six-Sigma, QFD, Taguchi methods and TQM- Data warehousing and data mining in business excellence- Measuring performance in creative industries- Best practices in creative economy and industries
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